688166: simplified equity change report

Borui biomedicine (Suzhou) Co., Ltd

Simplified equity change report

Name of listed company: Borui biomedicine (Suzhou) Co., Ltd. stock listing place: Shanghai Stock Exchange Stock abbreviation: Brightgene Bio-Medical Technology Co.Ltd(688166) Stock Code: 688166 information disclosure obligor: Sequoia Zhisheng equity investment partnership (limited partnership) in Ningbo Meishan free trade port area executive partner: Jiaxing Sequoia kunsheng investment management partnership (limited partnership)

Registered address: g0172, zone B, Room 401, building 1, No. 88, Qixing Road, Meishan, Beilun District, Ningbo, Zhejiang

Mailing address: 3606, building 3, Huamao Center office building, No. 77 Jianguo Road, Chaoyang District, Beijing

Nature of equity change: decrease in shares

Signed on: January 18, 2022

Statement of information disclosure obligor

1、 This report is prepared by the information disclosure obligor in accordance with the company law of the people’s Republic of China, the securities law of the people’s Republic of China, the measures for the administration of the acquisition of listed companies, the standards for the content and format of information disclosure by companies that publicly issue securities No. 15 – Report on changes in equity, and other relevant laws, regulations and departmental rules.

2、 The information disclosure obligor has obtained necessary authorization and approval for signing this report, and its performance does not violate or conflict with any provision in the articles of association or internal rules of the information disclosure obligor.

3、 In accordance with the provisions of the securities law of the people’s Republic of China, the measures for the administration of the acquisition of listed companies and the standards for the contents and forms of information disclosure by companies offering securities to the public No. 15 – Report on changes in equity, this report has fully disclosed the changes in shares in which the information disclosure obligor has interests in Borui biomedical (Suzhou) Co., Ltd. As of the signing date of this report, except for the shareholding information disclosed in this report, the above information disclosure obligor has not increased or reduced its shares in Borui biomedical (Suzhou) Co., Ltd. by any other means.

4、 This equity change is based on the information stated in this report. The information disclosure obligor has not entrusted or authorized any other person to provide information not listed in this report and make any explanation or explanation to this report.

catalogue

Section 1 introduction of information disclosure obligor Section II purpose of equity change and shareholding plan Section III change of rights and interests of information disclosure obligors Section IV trading of shares of Listed Companies in the first six months Section V other major matters Section VI documents for future reference eleven

interpretation

Unless otherwise specified, the following abbreviations are interpreted as follows in this report:

Listed company / company refers to Borui biomedical (Suzhou) Co., Ltd

Information disclosure obligor / Sequoia Zhisheng refers to Sequoia Zhisheng equity investment partnership Shengye (limited partnership) in Ningbo Meishan free trade port area

This equity change means that the proportion of shares held by Sequoia Zhisheng in the listed company is reduced to

Below 5.00%

This report refers to the simplified equity change report of Borui biomedical (Suzhou) Co., Ltd

Company law means the company law of the people’s Republic of China

Securities Law means the securities law of the people’s Republic of China

The acquisition Measures refer to the administrative measures for the acquisition of listed companies

Standard No. 15 refers to Standard No. 15 on the contents and forms of information disclosure by companies offering securities to the public – Report on changes in equity

Listing Rules refer to the Listing Rules of Shanghai Stock Exchange’s Sci tech innovation board

CSRC refers to the China Securities Regulatory Commission

Shenzhen Stock Exchange / stock exchange refers to Shanghai Stock Exchange

Yuan means RMB yuan

Note: 1 Any discrepancy between the total number and the mantissa of the sum of the sub item values in this report is caused by rounding; 2. The shareholding ratio in this report is calculated based on the total share capital of the company of 41000000 shares.

Section I Introduction to information disclosure obligors

1、 Basic information of information disclosure obligor

Name of information disclosure obligor: Ningbo Meishan free trade port Sequoia Zhisheng equity investment partnership (limited partnership)

Domicile / registered address: Zone B, Room 401, building 1, No. 88, Qixing Road, Meishan, Beilun District, Ningbo City, Zhejiang Province

G0172

Registered capital: RMB 7501 million

Mailing address: 3606, building 3, Huamao Center office building, No. 77, Jianguo Road, Chaoyang District, Beijing

Executive partner: Jiaxing Sequoia kunsheng investment management partnership (limited partnership)

Unified social credit code 91330206ma2935ap7d

Type of enterprise: limited partnership

Business scope: equity investment and related consulting services (without the approval of financial and other regulatory authorities, it is not allowed to engage in financial businesses such as deposit taking, financing guarantee, customer financing and capital collection (financing) from the public) (for projects that need to be approved according to law, business activities can be carried out only with the approval of relevant departments)

Jiaxing Sequoia kunsheng investment management partnership (limited partnership) of major shareholders or sponsors

Name: Ningbo Meishan free trade port area Sequoia Mingsheng equity investment partnership (limited partnership)

Sequoia Jiasheng equity investment partnership (limited partnership) in Ningbo Meishan free trade port area

Operation period: August 9, 2017 to August 8, 2029

Date of establishment: August 9, 2017

2、 Information about the principal of the information disclosure obligor

Information disclosure: name, gender, nationality, long term residence or absence of overseas ID number

Residence right of the obligor

No 420106 ****** executive affairs partner Sequoia Zhisheng Zhou Kui, male, appointed representative of Chinese

3、 Information disclosure obligors hold and control more than 5% of the issued shares of other listed companies

As of the signing date of this report, the information disclosure obligor holds more than 5% shares of other listed companies in China: 7.40741% shares of Marssenger Kitchenware Co.Ltd(300894) (300894); Holds 6.56620% shares of Shenzhen Bioeasy Biotechnology Co.Ltd(300942) (300942).

Section II purpose of equity change and shareholding plan

1、 Purpose of this equity change of information disclosure obligor

According to its capital needs, the information disclosure obligor will reduce part of its shares in the company through centralized bidding and block trading from November 2, 2021 to January 17, 2022.

2、 Shareholding plan of information disclosure obligor in the next 12 months

After this equity change, the information disclosure obligor intends to continue to reduce its shares in the company in accordance with relevant laws, regulations and normative documents in the next 12 months. In the next 12 months, in case of relevant equity changes, the information disclosure obligor will timely perform the information disclosure obligations in accordance with the provisions of relevant laws.

Section III changes in rights and interests of information disclosure obligors

1、 Shareholding of information disclosure obligor

On September 16, 2021, the company disclosed the announcement of Borui biomedical (Suzhou) Co., Ltd. on the share reduction plan of shareholders holding more than 5% (Announcement No.: 2021-063). On the date of disclosure of the aforesaid announcement, the information disclosure obligors held 28724875 shares of the listed company, of which 8287956 shares were listed and circulated on November 9, 2020, This part of tradable shares with unlimited sales conditions accounts for 2.02145% of the total share capital of the company; On December 3, 2021, the company disclosed the announcement on the listing and circulation of some restricted shares issued by Borui biomedical (Suzhou) Co., Ltd. (Announcement No.: 2021-081). The information disclosure obligors held a total of 13624613 shares of the listed company, which were listed and circulated on December 10, 2021, accounting for 3.32308% of the total share capital of the company; So far, the information disclosure obligors have held 6812306 tradable shares of the listed company with limited sales conditions, accounting for 1.66154% of the total share capital of the company. As of the signing date of this report, the information disclosure obligors hold 20499801 shares of the company, accounting for 4.99995% of the company’s total existing share capital (retain the five decimal places and round the last one)

2、 Basic information of this equity change

From November 2, 2021 to November 24, 2021, Sequoia Zhisheng reduced 4392800 shares of the company through block trading, accounting for 1.07141% of the total share capital of the company. On November 26, 2021, the company disclosed the progress announcement of Borui biomedical (Suzhou) Co., Ltd. on the reduction of more than half the number of shareholders holding more than 5% and up to 1% (Announcement No.: 2021-080); From November 26, 2021 to January 17, 2022, Sequoia Zhisheng reduced a total of 3832274 shares of the company through block trading and centralized bidding, accounting for 0.93470% of the total share capital of the company.

As of the signing date of this report, the information disclosure obligors hold 20499801 shares of the company, accounting for 4.99995% of the total share capital of the company (retain the five decimal places and round the last one).

The details of this equity change are as follows:

Reduction ratio before equity change and after equity change

Number of holdings during the reduction period

Total number of shareholding (shares) mode of shareholding total number of shareholding (shares) proportion (%) (shares) proportion

Red 7.006 November 2, 2021 bulk 4.9999 shan28724875 – December 22 7111100 1.73441 transaction 20499801

07% 5%

Wisdom will be concentrated on December 24, 2021

SHENGRI – January 17, 2022 1113974 0.27170 bidding

day

Note: the shareholding ratio before and after this equity change shall be kept to five decimal places, and the last one shall be rounded.

3、 Restrictions on the rights of the obligor of the information discloser to own equity shares in the listed company

As of the signing date of this report, 13687495 shares of listed companies held by information disclosure obligors are tradable shares with unlimited sales conditions, and 6812306 shares of listed companies held by information disclosure obligors are tradable shares with limited sales conditions. There are no restrictions on the transfer of rights such as pledge, seizure or freezing.

Section IV trading of shares of Listed Companies in the first six months

The information disclosure obligor did not increase its holdings of shares of the listed company within 6 months before the signing date of this report, and only reduced its holdings of non restricted tradable shares of the listed company through centralized bidding trading and block trading. The reduction price range is 30.97 yuan / share to 37.3 yuan / share. The specific reduction is as follows:

Before equity change

Number of shareholders’ holdings during the period of reduction

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