Guangdong Hybribio Biotech Co.Ltd(300639) : Announcement on the company and its wholly-owned subsidiaries obtaining the notice of granting invention patent right

Securities code: 300639 securities abbreviation: Guangdong Hybribio Biotech Co.Ltd(300639) Announcement No.: 2022-004 Guangdong Hybribio Biotech Co.Ltd(300639)

Announcement on the company and its wholly-owned subsidiaries obtaining the notice of granting invention patent right

The company and all members of the board of directors guarantee that the information disclosed is true, accurate and complete without false records, misleading statements or major omissions.

Recently, Guangdong Hybribio Biotech Co.Ltd(300639) (hereinafter referred to as “the company” or ” Guangdong Hybribio Biotech Co.Ltd(300639) “) and its wholly-owned subsidiaries Chaozhou Guangdong Hybribio Biotech Co.Ltd(300639) Chemical Co., Ltd. (hereinafter referred to as “Kaipu chemical”) and Guangzhou Kaipu Pharmaceutical Technology Co., Ltd. (hereinafter referred to as “Kaipu pharmaceutical”) have received the Notice of awarding patent right for invention issued by the State Intellectual Property Office. The details are as follows:

Name of invention creation application No. / patent No. patent type patent application date patentee No

Guangdong Hybribio Biotech Co.Ltd(300639) , a-thalassemia phase, October 2021

1 202111249819.8 Kaipu chemical and related gene detection kit for invention patent 26

Kemp medicine

The acquisition of the above invention patent right will not have a significant impact on the company’s current business situation, but it is conducive to further improve the company’s intellectual property system, give full play to the company’s intellectual property advantages, promote the continuous enrichment of the company’s product structure and enhance the company’s core competitiveness.

The company will go through the registration formalities in strict accordance with the contents of the notice for going through the registration formalities. After going through the registration formalities on schedule, the State Intellectual Property Office will make a decision to grant the patent right, issue the invention patent certificate, register and announce it. The patent right will take effect from the date of announcement and be valid for 20 years from the date of application.

It is hereby announced.

Guangdong Hybribio Biotech Co.Ltd(300639) board of directors January 15, 2002

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