Wanbangde Pharmaceutical Holding Group Co.Ltd(002082) : summary of 2021 Annual Report

Securities code: Wanbangde Pharmaceutical Holding Group Co.Ltd(002082) securities abbreviation: Wanbangde Pharmaceutical Holding Group Co.Ltd(002082) Announcement No.: 2022015 Wanbangde Pharmaceutical Holding Group Co.Ltd(002082)

Summary of annual report 2021

1、 Important note: the summary of this annual report comes from the full text of the annual report. In order to fully understand the company’s operating results, financial status and future development plan, investors should carefully read the full text of the annual report in the media designated by the CSRC. In addition to the following directors, other directors attended the meeting of the board of directors to consider the annual report in person

Name of director not present in person position of director not present in person reason for not attending the meeting name of the entrusted person

Tips on non-standard audit opinions □ applicable √ not applicable to the profit distribution plan of common shares or the plan of converting accumulation fund into share capital in the reporting period considered by the board of directors √ applicable □ not applicable whether to convert accumulation fund into share capital □ yes √ no

The company’s profit distribution plan for ordinary shares reviewed and approved by the board of directors is: take 613222829 as the base, distribute cash dividends of 0.00 yuan (including tax) to all shareholders for every 10 shares, send bonus shares of 0 shares (including tax), and do not use the accumulation fund to increase the share capital. Preferred stock profit distribution plan for the reporting period adopted by the board of directors □ applicable √ not applicable II. Basic information of the company 1. Company profile

Stock abbreviation Wanbangde Pharmaceutical Holding Group Co.Ltd(002082) stock code Wanbangde Pharmaceutical Holding Group Co.Ltd(002082)

Shenzhen Stock Exchange

Contact person and contact information secretary of the board of directors securities affairs representative

Name: liutongke Jiangjian

Office address: Baizhang North Road, Chengdong street, Wenling City, Taizhou City, Zhejiang Province

28, 28

Fax: 057686183897

Tel: 057686183899057686183925

E-mail [email protected]. [email protected].

2. Introduction to main business or products during the reporting period

(I) main business and products

1. Pharmaceutical manufacturing industry

Pharmaceutical manufacturing business is mainly engaged in the R & D, production and sales of modern traditional Chinese medicine, chemical APIs and chemical agents. It has a perfect drug R & D, production and sales system, a complete industrial chain from traditional Chinese medicine extraction, API synthesis to the production of various dosage forms, and 184 drug production approval numbers. Its products involve many treatment fields such as cardiovascular, cerebrovascular, nervous system, respiratory system and digestive system diseases.

Ginkgo biloba dropping pills, the leading product of cardiovascular and cerebrovascular system, is a drug for the prevention and treatment of cardiovascular and cerebrovascular diseases. It is an exclusive dosage form variety with independent intellectual property rights and a national secondary protected variety of traditional Chinese medicine. It has been listed in the torch project of the Ministry of Science and technology, the national protected variety of traditional Chinese medicine, the national medical insurance catalogue and the national catalogue of essential drugs.

Huperzine A, the leading product of nervous system, is one of the most effective drugs to improve cognitive function and memory impairment and treat Alzheimer’s disease. Huperzine a developed by the company is the first product in China and has won the second prize of national technological invention.

Bromhexin hydrochloride, the leading product of respiratory system, is one of the three most widely used expectorant drugs in clinical application at present. Wanbangde Pharmaceutical Holding Group Co.Ltd(002082) pharmaceutical is the drafting unit of the national drug standard for bromhexin hydrochloride API and preparation. Relying on the integrated advantages of bromhexin hydrochloride API and preparation, it occupies the first place in China’s market share. Biphenyl diester dropping pills, the leading product of digestive system, is a common drug for the treatment of viral hepatitis and the increase of transaminase caused by drug-induced liver injury. It has won the title of “high-quality product in Zhejiang Province”, and its market share ranks in the forefront among the same products in China.

Clozapine, chlorpromazine and sulpiride, the leading products of the mental system, are antipsychotics. They are used to treat excitement, agitation and hallucinations caused by schizophrenia, mania or other psychotic disorders. They also have a certain curative effect on depressive symptoms and have a strong competitive advantage.

The main products of pharmaceutical manufacturing sector are as follows:

Serial number drug name schematic diagram function indications (indications)

Promoting blood circulation, removing blood stasis and dredging collaterals. It is used for chest arthralgia, heartache, stroke, 1 hemiplegia caused by blood stasis and obstruction of collaterals, and strong tongue; Patients with stable angina pectoris and cerebral infarction of coronary heart disease see the above symptoms.

Huperzine A

It is suitable for benign memory impairment and improves the ability of patients to point to memory, associative learning, image recall, meaningless graphic recognition and portrait recall. It can also improve the memory impairment caused by dementia patients and brain organic diseases.

In addition, this product is also used for the treatment of myasthenia gravis.

3 huperzine A injection

4 bromohexidine hydrochloride

It is mainly used for patients with sticky sputum caused by chronic bronchitis and asthma.

5 bromohexidine hydrochloride tablets

This product is suitable for bronchial asthma, asthmatic bronchitis and chronic zhiqihexin capsule bronchitis.

7 cefaclor granules this product is mainly applicable to respiratory system, urinary system, otolaryngology, skin and soft tissue infections caused by sensitive bacteria.

8 biphenyl diester

It is clinically used for patients with chronic persistent hepatitis with elevated ALT, and can also be used for elevated ALT caused by chemical poisons and drugs.

9 biphenyl diester dropping pills

Acute spasmodic pain caused by digestive system and biliary tract dysfunction caused by phloroglucinol injection; Acute spasmodic urethral, bladder and renal colic; Gynecological spasmodic pain

Omeprazole enteric sol is suitable for intestinal ulcer, duodenal ulcer, stress ulcer, reflux cystic esophagitis and Zhuoyi syndrome (gastrinoma)

Cimetidine Tablets are used to relieve stomach pain, heartburn (heartburn) and acid reflux caused by excessive gastric acid.

Clozapine is effective in controlling hallucinations, delusions and agitation in psychosis, and is clinically used in patients with agitation.

14 clozapine tablets

It has a good effect on the symptoms of positive 15 chlorpromazine hydrochloride tablets, such as excitement, agitation, hallucination, delusion, thinking disorder and behavior disorder. It is used for schizophrenia, mania or other psychotic disorders, anti vomiting, vomiting or intractable hiccup caused by various reasons.

It is a raw material drug of sulpiride tablets. Its indications are that it has a good effect on indifference, withdrawal, numbness, 16 sulpiride depression, hallucinations and delusions. It is suitable for the isolation, withdrawal and anxiety of simple type, paranoid type, tension type and chronic schizophrenia Indifferent symptoms. It has a certain effect on depressive symptoms.

It is used to prevent and treat calcium deficiency diseases, such as osteoporosis, hand foot convulsion, 17 calcium citrate tablets, bone hypoplasia, rickets, and calcium supplement for children, pregnant and lactating women, menopausal women and the elderly.

Water loss caused by various causes, including hypotonic, isosmotic and high Sodium Chloride Injection (dual osmotic dehydration), hyperosmolar non ketonic diabetic coma, application of isotonic or low 18 valve, sodium chloride can correct the condition of loss of water and hypertonic state. Low chlorine metabolic alkalosis; Wash eyes and wounds with normal saline externally; It is also used for water sac induction of labor in obstetrics.

19 artificial bezoar metronidazole for acute dementia

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