Yifan Pharmaceutical Co.Ltd(002019) : summary of 2021 Annual Report

Securities code: Yifan Pharmaceutical Co.Ltd(002019) securities abbreviation: Yifan Pharmaceutical Co.Ltd(002019) Announcement No.: 2022024 Yifan Pharmaceutical Co.Ltd(002019) 2021 annual report summary

1、 Important note: the summary of this annual report comes from the full text of the annual report. In order to fully understand the company's operating results, financial status and future development plan, investors should carefully read the full text of the annual report in the media designated by the CSRC. In addition to the following directors, other directors attended the meeting of the board of directors to consider the annual report in person

Name of director not present in person position of director not present in person reason for not attending the meeting name of the entrusted person

Tips on non-standard audit opinions □ applicable √ not applicable to the profit distribution plan of common shares or the plan of converting accumulation fund into share capital in the reporting period considered by the board of directors √ applicable □ not applicable whether to convert accumulation fund into share capital □ yes √ no

The company's profit distribution plan for ordinary shares reviewed and approved by the board of directors is: take 123410607700 as the base, distribute cash dividends of 0.00 yuan (including tax) to all shareholders for every 10 shares, send bonus shares of 0 share (including tax), and do not use the accumulation fund to increase the share capital. Profit distribution plan for preferred shares adopted by the board of directors during the reporting period □ applicable √ not applicable II. Basic information of the company 1. Company profile

Stock abbreviation Yifan Pharmaceutical Co.Ltd(002019) stock code Yifan Pharmaceutical Co.Ltd(002019)

Shenzhen Stock Exchange

Contact person and contact information secretary of the board of directors securities affairs representative

Name: Feng Deqi, Li Lei

Office address: intersection of Jinxiu Avenue and qinglongtan Road, economic development zone, Hefei, Anhui, Yifan Pharmaceutical Co.Ltd(002019) intersection, Yifan Pharmaceutical Co.Ltd(002019)

Fax: 055162652019

Tel: 055162672019055162652019

E-mail [email protected]. [email protected].

2. Introduction to main business or products during the reporting period

(I) main business of the company

During the reporting period, the company was mainly engaged in the R & D, production, sales and drug promotion services of pharmaceutical products, APIs and polymer materials. According to the guidelines for Industry Classification of listed companies (revised in 2012) issued by the CSRC, the company belongs to pharmaceutical manufacturing

Industry. Medical products mainly include blood tumors, gynecology, pediatrics, skin and other drugs; The bulk drug is mainly vitamins

B5 and original B5 products; Polymer materials mainly include PBS and PVB products.

The main products are as follows:

Product category product sales area indication remarks

The English trade name "Zometa" and the Chinese trade name "Zetai" are used together with standard antitumor drugs,

Zoledronic acid concentrated solution for injection is sold abroad to treat bone damage in patients with solid tumor bone metastasis and multiple myeloma. Used to cure evil

Hypercalcemia caused by malignant tumor (HCM)

Thymosin for injection- α 1. Thymosin in overseas sales α 1. It plays the role of immunomodulatory cooperative agent in the treatment of malignant tumors, hepatitis and other immune deficiency diseases

Ararubicin hydrochloride for injection is sold in China for acute leukemia and malignant lymphoma, and can also be used in the cooperative sale of other solid malignant tumors. Vincristine sulfate injection is sold in China for the treatment of acute and chronic leukemia Cooperative sales such as the treatment of malignant lymphoma for the prevention and treatment of life-threatening or vision impaired patients infected with cytomegalovirus, and

Ganciclovir for injection is sold in China as an import agent for preventing organ transplant patients related to cytomegalovirus infection

Melphalan tablets are sold in China and are applicable to the import agent for the treatment of multiple myeloma and advanced ovarian adenocarcinoma

Retinoic acid tablets are sold in China for the treatment of acute promyelocytic leukemia

Compound Huangdai tablets are sold in China, clearing away heat and detoxification, supplementing qi and generating blood. Acute promyelocytic leukemia for initial treatment

Sales in oxytocin Nasal Spray can enhance uterine contraction and promote contraction of smooth muscle cells around the breast.

It can be used to assist the discharge of milk secreted by postpartum mammary gland

Fuyinkang lotion is sold in China and is used for acute and chronic urethritis, vaginitis, pelvic inflammation and prostate cancer caused by Mycoplasma, chlamydia and gonococcus

inflammation

Yifu Kunning granule sold in China has the function of promoting blood circulation and Qi, hemostasis and regulating menstruation.

It is used in women with menorrhagia and blood stasis

Yao erchang

The product of toloterol patch is sold in China under the trade name of "amidi", which is used to alleviate the symptoms of dyspnea caused by airway obstructive diseases such as bronchial asthma, acute bronchitis, chronic bronchitis and lung qi swelling

Fuyan rehabilitation tablets are sold in China to treat common gynecological diseases and regulate normal vaginal flora

Xiaoer Qingqiao granule is sold in China, which can dispel wind and clear potential, detoxify and benefit pharynx, reduce swelling and relieve pain. Used for wind heat milk moth; Evidence: fever, sore throat, laryngeal nucleus

Swelling, red tongue, yellow fur, etc; It is mainly used for children with acute tonsillitis (acute milk moth) with the above syndrome

Emestine fumarate sustained release adhesive is sold in China for allergic rhinitis and urticaria

bag

It is a synthetic corticosteroid agent used to treat various skin diseases or reduce the discomfort caused by mouth ulcers

Skin scar antipruritic softening cream is sold in China and is used for burns or proliferative scars after surgery

This kind of dehumidification and antipruritic ointment is sold in China and is used for the adjuvant treatment of acute and subacute eczema with damp heat or dampness resistance

Piminxiao capsule is sold in China to dispel wind and dampness, clear away heat and detoxify, cool blood and relieve itching. It is used for acute and chronic urticaria and acute eczema, belonging to wind heat syndrome or self owned

Wind heat dampness syndrome

The company has a full range of human insulin injections. The human insulin produced by recombinant DNA technology has the same structure and function as the domestic and overseas natural insulin of human insulin injections except Poland. It can regulate glucose metabolism, promote the global market sales of liver, bone and adipose tissue, absorb and utilize glucose, promote the conversion of glucose into glycogen, store it in muscle and liver, and inhibit the field

Secrete gluconeogenesis to reduce blood sugar

Class I recombinant human growth hormone for injection is sold abroad and used as an agent for growth hormone deficiency in children and adults, Turner's syndrome and chronic renal insufficiency in children

Growth disorders, surgery, post-traumatic hypermetabolism (negative nitrogen balance), burns, sepsis

Hufufang Yinhua Jiedu granules are sold in China to relieve wind and relieve surface, clear away heat and detoxify. It is used for common cold and epidemic fever.

Slight wind, headache, stuffy nose, runny nose, cough, sore throat, whole body pain, thin white or yellowish fur, floating pulse number

It is similar to clearing lung and resolving phlegm, relieving cough and asthma. It is used for acute bronchitis and chronic bronchitis. The acute attack belongs to phlegm heat depression

Maqin Xiaoke granule sells lung syndrome in China. The symptoms are cough, wheezing, yellow or thick phlegm, fever, dry mouth, yellow and greasy fur, red tongue and so on

Pudilan anti-inflammatory tablets are sold in China, clearing away heat and detoxification, anti-inflammatory and detumescence. For furuncle, pharyngitis and tonsillitis

Lactulose oral solution is sold in China. It is an oral preparation for the treatment of constipation, prevention and treatment of hepatic encephalopathy. It is imported as an agent to promote blood circulation, remove blood stasis, regulate qi and relieve pain. It is used for coronary heart disease with tired angina pectoris with qi stagnation and blood stasis syndrome, including chest pain, chest tightness and angina pectoris

He Yandan capsule domestic sales panic, suffocation and so on

class

Vancomycin hydrochloride for injection is sold abroad, which is suitable for serious infection of Gram-positive bacteria resistant to penicillin and cephalosporin

Also known as calcium d-pantothenate, it is the precursor of coenzyme A and participates in the metabolism of carbohydrates, proteins and fats

Vitamin B5 is used worldwide. It is an indispensable and irreplaceable substance for human body and animals to maintain normal physiological functions. It is a kind of heavy metal

Original feed additives and food additives

Provitamin B5, also known as d-panthenol in the world, is an excellent skin and hair protector, which is mainly used in food, medicine and cosmetics

Additives and nutritional supplements for liquid preparations in food and beverage industry

Polybutylene succinate was synthesized by condensation polymerization from high succinic acid and butanediol

European PBS) is a fully biodegradable material with good comprehensive performance, which is used for packaging, tableware, cosmetic bottles and self owned products

Sub PBS medicine bottle, disposable

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