Shanghai Pharmaceuticals Holding Co.Ltd(601607) : Shanghai Pharmaceuticals Holding Co.Ltd(601607) independent director's special statement on guarantee matters in 2021

Special notes of independent directors on guarantees in 2021

In 2021, the total amount of guarantee completed by the company and its subsidiaries within the scope of consolidated statements was 12009516500 yuan (the guarantee amount was converted according to the shareholding ratio of the company, without considering the guarantee completed by the newly acquired subsidiaries before the merger this year, the same below), of which: the guarantee completed by the company as a subsidiary was 5644456700 yuan, The holding company of the company is an associated company, and the completed guarantee amount is 109864 million yuan. The completed guarantee amount between companies within the scope of the consolidated statements of the company is 63540734 million yuan.

As of December 31, 2021, the outstanding guarantee amount of the company and its subsidiaries within the scope of consolidated statements totaled 8503520300 yuan, of which the outstanding guarantee amount of the company for its subsidiaries was 4788810600 yuan, mainly due to the medium and long-term M & A financing guarantee provided by the company to reduce the financing cost of overseas M & A platforms, The outstanding guarantee amount between companies within the scope of the consolidated statements of the company is 37147097 million yuan.

The decision-making procedures of the company's external guarantee within the scope of the consolidated statements of the company and its subordinates comply with the provisions of relevant laws, regulations, rules and the articles of association.

(this page is the signature page of Shanghai Pharmaceuticals Holding Co.Ltd(601607) independent director's special instructions and independent opinions on the guarantee matters in 2021) independent director: Cai Jiangnan independent director: Hong Liang independent director: Gu Chaoyang independent director: Huo Wenxun

Shanghai Pharmaceuticals Holding Co.Ltd(601607) March 29, 2002 (this page is the signature page of Shanghai Pharmaceuticals Holding Co.Ltd(601607) independent directors' special instructions and independent opinions on the guarantee matters in 2021) independent director: Cai Jiangnan independent director: Hong Liang independent director: Gu Chaoyang independent director: Huo Wenxun

Shanghai Pharmaceuticals Holding Co.Ltd(601607) March 29, 2002 (this page is the signature page of Shanghai Pharmaceuticals Holding Co.Ltd(601607) independent directors' special instructions and independent opinions on the guarantee matters in 2021) independent director: Cai Jiangnan independent director: Hong Liang independent director: Gu Chaoyang independent director: Huo Wenxun

Shanghai Pharmaceuticals Holding Co.Ltd(601607) March 29, 2002 (this page is the signature page of Shanghai Pharmaceuticals Holding Co.Ltd(601607) independent directors' special instructions and independent opinions on the guarantee matters in 2021) independent director: Cai Jiangnan independent director: Hong Liang independent director: Gu Chaoyang independent director: Huo Wenxun

Shanghai Pharmaceuticals Holding Co.Ltd(601607) March 29, 2002

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