Company code: Jenkem Technology Co.Ltd(688356) company abbreviation: Jenkem Technology Co.Ltd(688356) Jenkem Technology Co.Ltd(688356)
Annual report for 2021
Important tips
1、 The board of directors, board of supervisors, directors, supervisors and senior managers of the company guarantee the authenticity, accuracy and integrity of the contents of the annual report, and there are no false records, misleading statements or major omissions, and bear individual and joint legal liabilities. 2、 III. when the company is not profitable and not yet listed √ yes
The company has elaborated various risks and countermeasures that the company may face in the process of operation in this report. Please refer to section III "management discussion and analysis" of this report. 4、 All directors of the company attended the board meeting. 5、 The special audit opinion issued by PricewaterhouseCoopers LLP is unqualified
Sue. 6、 Xu Zhao, the company's principal, Han Lei, the person in charge of accounting, and Li Chunlei, the person in charge of accounting organization (Accounting Supervisor), declare that they guarantee the authenticity, accuracy and completeness of the financial report in the annual report. 7、 The profit distribution plan or the plan of converting accumulation fund into share capital in the reporting period adopted by the resolution of the board of directors
The company's profit distribution plan for 2021 is as follows: the company plans to distribute cash dividends of 8.79 yuan (including tax) to all shareholders for every 10 shares based on the total share capital on the date of equity registration of dividend distribution in 2021, and the total amount of cash dividends is expected to be 5274000000 yuan, accounting for 30% of the net profit attributable to shareholders of Listed Companies in the consolidated statements of the company in 2021; The company does not convert the capital reserve into share capital and does not give bonus shares. The amount of cash dividends in the above profit distribution plan for 2021 is temporarily calculated based on the current total share capital of the company of Shanghai Pudong Development Bank Co.Ltd(600000) 00 shares, and the total amount of cash dividends actually distributed will be calculated based on the total share capital on the registration date of dividends and dividends in 2021. The company's 2021 profit distribution plan has been deliberated and approved at the 17th meeting of the second board of directors of the company, and needs to be deliberated and approved by the 2021 annual general meeting of shareholders of the company. 8、 Whether there are important matters such as special arrangements for corporate governance □ applicable √ not applicable IX. risk statement of forward-looking statements √ applicable □ not applicable
The company's future plans, development strategies and other forward-looking statements involved in this report do not constitute the company's substantive commitment to investors. Investors are reminded to pay attention to investment risks.
10、 Whether there is any non operational occupation of funds by the controlling shareholders and their related parties no Xi. Whether there is any external guarantee in violation of the specified decision-making procedures no XII. Whether more than half of the directors cannot guarantee the authenticity, accuracy and completeness of the annual report disclosed by the company no XIII. Others □ applicable √ not applicable
catalogue
Section 1 interpretation Section 2 company profile and main financial indicators Section III Management Discussion and Analysis Section IV corporate governance Section V environment, social responsibility and other corporate governance 54 section VI important matters Section VII changes in shares and shareholders 96 Section VIII preferred shares Section IX corporate bonds 115 section x financial reporting one hundred and sixteen
Include the person in charge of the company, the person in charge of accounting and the person in charge of the accounting organization (the person in charge of Accounting)
Financial statements signed and sealed by the document catalogue for future reference
The original of the audit report with the seal of the accounting firm and the signature and seal of the certified public accountant
Originals of all company documents and announcements publicly disclosed during the reporting period
Section I interpretation
1、 Interpretation in this report, unless the context otherwise requires, the following words have the following meanings: Interpretation of common words
The company, company, joint stock company, key refers to Jenkem Technology Co.Ltd(688356)
Kai technology, Jiankai Co., Ltd., Beijing Jiankai
Tianjin Jiankai refers to Tianjin Jenkem Technology Co.Ltd(688356) Co., Ltd., a wholly-owned subsidiary of Jenkem Technology Co.Ltd(688356) company
Liaoning Jiankai refers to Liaoning Jenkem Technology Co.Ltd(688356) Co., Ltd., a wholly-owned subsidiary of Jenkem Technology Co.Ltd(688356) company
American keykey refers to jenkem Technology USA Inc., a Jenkem Technology Co.Ltd(688356) wholly-owned subsidiary
Shanghai manlu refers to Shanghai manlu investment management partnership (limited partnership)
Shuimu development means Shuimu development limited
Tianyi Xihui refers to Beijing Tianyi Xihui Investment Management Center (limited partnership)
Guojun chuangchuang No. 3 refers to Shanghai Guojun chuangchuang No. 3 equity investment partnership (limited partnership)
Key industry Tengfei refers to Beijing key industry Tengfei enterprise management consulting center (limited partnership)
Xiamen Amoytop Biotech Co.Ltd(688278) refers to Xiamen Amoytop Biotech Co.Ltd(688278) ( Xiamen Amoytop Biotech Co.Ltd(688278) . SH)
Accountants, accounting firms and PwC refer to PwC Zhongtian Certified Public Accountants (special general partnership)
Yongdao
Reporting period refers to 2021
The end of the reporting period refers to December 31, 2021
Yuan and 10000 yuan refer to RMB yuan and 10000 yuan
Peg refers to polyethylene glycol, Chinese Name: polyethylene glycol
MPEG refers to methoxy polyethyleneglycol, Chinese Name: methoxy polyethylene glycol
A derivative of polyethylene glycol that is chemically active, usually by reaction
Dispersion refers to polydispersity, also known as polydispersity index, which is used to measure the molecular weight distribution of polymers in polymer chemistry
Molecular weight refers to the relative molecular weight, that is, the sum of the relative atomic mass of each atom in the chemical formula
Biocompatibility refers to the reaction of living tissue to inactive materials. Materials with good biocompatibility are suitable for making medical devices or drugs involved in human body
Polypeptide refers to a compound in which amino acids are linked together by peptide bonds
Cytokines refer to a class of small molecular proteins with extensive biological activities synthesized and secreted by immune cells (such as monocytes, macrophages, T cells, B cells, NK cells, etc.) and some non immune cells (endothelial cells, epidermal cells, fibroblasts, etc.)
Immunogenicity refers to the performance that can cause immune response, and the characteristics that antigen can stimulate specific immune cells, activate, proliferate and divide immune cells, and finally produce immune effector antibodies and sensitized lymphocytes
Small molecule drugs refer to chemically synthesized drugs, usually organic compounds with molecular weight less than 1000
Preclinical study refers to a research stage before clinical trial, during which important safety evaluation and other data will be collected
Phase II clinical trial refers to the preliminary evaluation stage of therapeutic effect.
The purpose is to preliminarily evaluate the therapeutic effect and safety of drugs on patients with target indications, and also to provide basis for the design of phase III clinical trial and the determination of dosage scheme.
The research design at this stage can take many forms according to the specific research purpose, including randomized blind controlled clinical trial
Phase III clinical trial refers to the confirmation stage of therapeutic effect. Its purpose is to further verify the therapeutic effect and safety of drugs on patients with target indications, evaluate the relationship between benefits and risks, and finally provide a basis for the review of drug registration applications
GMP refers to the abbreviation of good manufacturing practice. It is the standard of drug production quality management. It is the basic standard of drug production and quality management. China is currently implementing GMP standards
CGMP refers to the abbreviation of current good manufacturing practice and dynamic drug production quality management specification. It is an international GMP implemented by countries or regions such as the European Union, Japan and the United States
Ich-q7 refers to the "guidelines for good manufacturing practices for APIs" designated by the International Coordinating Committee for injection technology for human use (ICH), which is applicable to the production of raw materials in ICH member countries. If the API is exported to member countries, it must also comply with the requirements of ich-q7
Class 1 new drugs refer to new drugs that are not listed at home and abroad
Class III medical devices refer to medical devices that have high risks and need to be strictly controlled and managed by special measures to ensure their safety and effectiveness
LNPS refer to lipid nanoparticles, a nucleic acid drug delivery system
Nucleic acid drugs include antisense nucleic acid (ASO), small interfering RNA (siRNA), messenger RNA (mRNA), aptamer, microRNA (miRNA), small activating RNA (Sarna), ribozyme, antibody nucleic acid coupled drug (ARC), etc. it is a form of gene therapy
Drug delivery system
