Shenzhen Salubris Pharmaceuticals Co.Ltd(002294) : internal control assurance report

Shenzhen Salubris Pharmaceuticals Co.Ltd(002294) internal control assurance report

Daxin zhuanshen Zi [2022] No. 500044

Daxin certified public accountants LLP

Wuyige certified public accountants LLP telephone: + 86 (10) 8233055822 / F, Xueyuan International Tower, No. 1 Zhichun Road, Haidian District, Beijing Fax: + 86 (10) 82327668 No. 1 Zhichun Road, Haidian dist, 22nd floor, College International Building com. cn. Postal Code: Beijing, China 100083

Internal control assurance report

Daxin zhuanshen Zi [2022] No. 500044 Shenzhen Salubris Pharmaceuticals Co.Ltd(002294) all shareholders:

We are entrusted to verify the effectiveness of internal control related to financial reporting of Shenzhen Salubris Pharmaceuticals Co.Ltd(002294) (hereinafter referred to as “your company”) on December 31, 2021.

1、 Management’s responsibility for internal control

The management of your company is responsible for designing, implementing and maintaining effective internal control and evaluating its effectiveness in accordance with relevant national laws and regulations.

2、 Responsibilities of Certified Public Accountants

Our responsibility is to express assurance opinions on the effectiveness of internal control based on the implementation of assurance work. We have carried out the assurance work in accordance with the provisions of other assurance business standards for Chinese certified public accountants No. 3101 – assurance business other than audit or review of historical financial information. The standard requires us to plan and implement assurance work to obtain reasonable assurance on whether the information of the assurance object is free from material misstatement. In the process of assurance, we have implemented other procedures including understanding, testing and evaluating the rationality of internal control design and the effectiveness of implementation, as well as other procedures we think necessary.

We believe that our assurance work provides a reasonable basis for expressing opinions.

3、 Inherent limitations of internal control

Internal control has inherent limitations, and there is the possibility of undetected misstatement due to error or fraud. In addition, changes in circumstances may lead to inappropriate internal control or reduce the degree of compliance with control policies and procedures,

Wuyige certified public accountants LLP telephone: + 86 (10) 8233055822 / F, Xueyuan International Tower, No. 1 Zhichun Road, Haidian District, Beijing Fax: + 86 (10) 82327668 No. 1 Zhichun Road, Haidian dist, 22nd floor, College International Building com. cn. Postal Code: Beijing, China 100083

According to the evaluation results of internal control, it is speculated that the effectiveness of internal control in the future has a certain risk.

4、 Assurance opinion

We believe that your company has maintained effective internal control over financial reporting in all major aspects as of December 31, 2021 in accordance with the basic norms of enterprise internal control and relevant regulations.

Daxin Certified Public Accountants (special general partnership) Chinese certified public accountant: Chen Jingpei

Beijing, China Certified Public Accountant: Liu Jiaona

March 25, 2002

Shenzhen Salubris Pharmaceuticals Co.Ltd(002294)

Internal control evaluation report in 2021

Shenzhen Salubris Pharmaceuticals Co.Ltd(002294) all shareholders:

In accordance with the provisions of the basic norms of enterprise internal control and its supporting guidelines and other internal control regulatory requirements (hereinafter referred to as the “enterprise internal control normative system”), combined with the internal control system and evaluation methods of the company (hereinafter referred to as the “company”), on the basis of daily and special supervision of internal control, We evaluated the effectiveness of the company’s internal control on December 31, 2021 (the benchmark date of the internal control evaluation report).

1、 Important statement

It is the responsibility of the board of directors of the company to establish, improve and effectively implement internal control, evaluate its effectiveness and truthfully disclose the internal control evaluation report in accordance with the provisions of the enterprise’s internal control standard system. The board of supervisors shall supervise the establishment and implementation of internal control by the board of directors. The management is responsible for organizing and leading the daily operation of the enterprise’s internal control. The board of directors, the board of supervisors and the directors, supervisors and senior managers of the company guarantee that there are no false records, misleading statements or major omissions in the contents of this report, and bear individual and joint legal liabilities for the authenticity, accuracy and completeness of the contents of the report.

The objective of the company’s internal control is to reasonably ensure the legal compliance of operation and management, asset safety, authenticity and integrity of financial reports and relevant information, improve operation efficiency and effect, and promote the realization of development strategy. Due to the inherent limitations of internal control, it can only provide reasonable assurance for the realization of the above objectives. In addition, as changes in circumstances may lead to inappropriate internal control or reduced compliance with control policies and procedures, there is a certain risk to speculate the effectiveness of internal control in the future according to the internal control evaluation results.

2、 Internal control evaluation conclusion

1. Does the company have any major defects in internal control over financial reporting on the benchmark date of internal control evaluation report

□ yes ☑ no

2. Evaluation conclusion of internal control over financial reporting

☑ Valid □ invalid

According to the identification of major defects in the company’s internal control over financial reporting, there are no major defects in the internal control over financial reporting on the benchmark date of the internal control evaluation report. The board of Directors believes that the company has maintained effective internal control over financial reporting in all major aspects in accordance with the requirements of the enterprise’s internal control standard system and relevant regulations.

3. Whether significant defects in internal control over non-financial reporting are found

□ yes ☑ no

According to the identification of major defects in the company’s internal control over non-financial reports, the company found no major defects in the company’s internal control over non-financial reports on the benchmark date of the internal control evaluation report.

4. Factors affecting the evaluation conclusion of internal control effectiveness from the base date of internal control evaluation report to the date of issuance of internal control evaluation report.

□ applicable ☑ Not applicable

3、 Internal control evaluation

(I) evaluation scope of internal control

According to the risk oriented principle, the company determines the main units, businesses and matters included in the evaluation scope and high-risk areas. 1. The main units included in the assessment include the parent company and all subsidiaries that are included in the scope of the assessment, including the parent company and all subsidiaries that are included in the scope of the merger, specifically as follows: Shenzhen Salubris Pharmaceuticals Co.Ltd(002294) company Nuotai International Co., Ltd.

2. Proportion of units included in the scope of evaluation:

Proportion of indicators%

The total assets of the units included in the evaluation scope account for 100% of the total assets in the company’s consolidated financial statements

The total operating income of the units included in the evaluation scope accounts for 100% of the total operating income in the company’s consolidated financial statements

3. The main operations and matters included in the scope of evaluation include:

Corporate Governance: organizational structure, development strategy, human resources, social responsibility and corporate culture; Business process level: capital activities, investment activities, sales management (accounts receivable), costs, engineering construction, procurement management, asset management (inventory and fixed assets), financial report preparation, related party transactions, comprehensive budget, contract management, information system, etc.

4. The high-risk areas of focus mainly include:

Accounts receivable management, inventory, engineering construction, major investment business, working capital, R & D risk, product quality risk, production management risk, financial reporting risk, human resources risk, safety risk, etc.

5. The above units, businesses and matters included in the evaluation scope and high-risk areas cover the main aspects of the company’s operation and management, and there are no major omissions.

(II) basis of internal control evaluation and identification standard of internal control defects

The company organizes and carries out internal control evaluation according to the enterprise internal control standard system and in combination with various internal systems, processes, guidelines and other relevant provisions of the company.

The board of directors of the company distinguished the internal control of financial report from the internal control of non-financial report according to the identification requirements for major defects, important defects and general defects of the enterprise internal control standard system, combined with the factors such as the company’s size, industry characteristics, risk preference and risk tolerance, and studied and determined the specific identification standards of internal control defects applicable to the company, which are consistent with the previous years. The identification standards of internal control defects determined by the company are as follows:

1. Identification criteria for defects in internal control over financial reporting

The quantitative criteria for the evaluation of internal control defects in financial reporting determined by the company are as follows:

The quantitative standard takes the total profit and total assets as the measurement indicators. If the loss that may be caused by the defect of internal control is related to the income statement, it shall be measured by the total profit index. If the amount of financial misstatement that may be caused by the defect alone or in combination with other defects is less than 1% of the total profit, it is recognized as a general defect; If it exceeds 1% but less than 5% of the total profit, it is an important defect; If it exceeds 5% of the total profit, it is recognized as a major defect.

Losses that may be caused or caused by internal control defects related to asset management shall be measured by the total asset index. If the amount of financial report misstatement that may be caused by the defect alone or in combination with other defects is less than 0.5% of the total assets, it is recognized as a general defect; If it exceeds 0.5% but less than 1% of the total assets, it is recognized as an important defect; If it exceeds 1% of the total assets, it is recognized as a major defect.

The qualitative criteria for the evaluation of internal control defects in financial reporting determined by the company are as follows:

Signs of significant deficiencies in financial reporting include:

1. The enterprise corrects the published financial report;

2. The certified public accountant finds that there is a material misstatement in the current financial report, but the internal control fails to find the misstatement in the operation process; 3. The supervision of the enterprise audit committee on the company’s external financial report and the internal control of financial report is invalid;

4. Failure of control environment at the company level.

Signs of significant deficiencies in financial reporting include:

1. The certified public accountant found that there was a general misstatement in the current financial report, but the internal control failed to find the misstatement in the operation process; 2. There are important defects in the supervision of internal control by enterprise audit committee and internal audit institutions.

General defects refer to other control defects other than the above major defects and important defects.

2. Identification standard of internal control defects in non-financial reporting

The quantitative criteria for the evaluation of internal control defects in non-financial reporting determined by the company are as follows:

The quantitative standard for the evaluation of internal control defects in non-financial reporting is that the amount of direct loss is less than 0.3% of the total assets, which is recognized as a general defect; If it is greater than 0.3% but less than 0.5% of the total assets, it is recognized as an important defect; If it is greater than 0.5% of the total assets, it is recognized as a major defect.

The qualitative criteria for the evaluation of internal control defects in non-financial reporting determined by the company are as follows:

Under the following circumstances, it can be identified as a major defect, and under other circumstances, it can be identified as a major defect or a general defect according to its degree of influence.

1. The lack of decision-making procedures leads to major mistakes;

2. Severe punishment for violation of national laws and regulations;

3. Serious loss of middle and senior managers and senior technicians;

4. Negative news frequently appeared in the media, which affected a wide range, attracted the attention of relevant departments and launched investigations;

5. Lack of system control or system failure of important business;

6. Fraud by directors, supervisors and senior managers;

7. Major defects in internal control have not been rectified.

(III) identification and rectification of internal control defects

1. Identification and rectification of internal control defects in financial reporting

According to the above identification standards of internal control defects in financial reporting, the company did not have major defects and important defects in internal control of financial reporting during the reporting period.

2. Identification and rectification of internal control defects in non-financial reports

According to the above identification standards of internal control defects in non-financial reports, no major defects in the company’s internal control over non-financial reports were found during the reporting period

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