Cansino Biologics Inc(688185) : special instructions and independent opinions of independent directors on the company’s external guarantee

Cansino Biologics Inc(688185) Jinyu Bio-Technology Co.Ltd(600201) company

The special instructions and independent opinions of the independent directors on the external guarantee of the company are in accordance with the company law of the people’s Republic of China, the securities law of the people’s Republic of China, the Listing Rules of the science and Innovation Board of Shanghai Stock Exchange, the rules for the listing of securities on the stock exchange of Hong Kong Limited and the rules for independent directors of listed companies Guidelines for the supervision of listed companies No. 8 – regulatory requirements for capital transactions and external guarantees of listed companies and other relevant laws, regulations and normative documents, as well as the relevant provisions of the articles of association of Cansino Biologics Inc(688185) Jinyu Bio-Technology Co.Ltd(600201) company (hereinafter referred to as the “articles of association”) and the working system of independent non-executive directors of Cansino Biologics Inc(688185) Jinyu Bio-Technology Co.Ltd(600201) company, As an independent director of Cansino Biologics Inc(688185) Jinyu Bio-Technology Co.Ltd(600201) company (hereinafter referred to as “the company”), we have carefully verified the external guarantee of the company in 2021. In a serious and responsible attitude and based on the principles of independence, prudence and objective judgment, we hereby express our independent opinions as follows:

During the reporting period, the company did not have any form of external guarantee, nor did it have any external guarantee that occurred in the previous period but lasted until the reporting period, and there was no situation that damaged the interests of the company and all shareholders, especially minority shareholders.

Independent directors: Wei Shaokun, Xin Zhu, GUI Shuifa, Liu Jianzhong March 25, 2022

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