Cansino Biologics Inc(688185) : Announcement on renewing the appointment of accounting firms

Securities code: Cansino Biologics Inc(688185) securities abbreviation: Cansino Biologics Inc(688185) Announcement No.: 2022018 Cansino Biologics Inc(688185) Jinyu Bio-Technology Co.Ltd(600201) company

Announcement on the renewal of accounting firm

The board of directors and all directors of the company guarantee that there are no false records, misleading statements or major omissions in the contents of this announcement, and bear legal responsibility for the authenticity, accuracy and integrity of its contents according to law.

Important content tips:

Cansino Biologics Inc(688185) Jinyu Bio-Technology Co.Ltd(600201) company (hereinafter referred to as "the company" or " Cansino Biologics Inc(688185) ") plans to renew Deloitte Touche Tohmatsu (special general partnership) (hereinafter referred to as "Deloitte Touche Tohmatsu") as the domestic audit institution and internal control audit institution in 2022, and Deloitte guanhuang Chenfang Certified Public Accountants (hereinafter referred to as "Deloitte Hong Kong") as the overseas audit institution in 2022.

1、 Basic information of the accounting firm to be renewed

The company plans to continue to employ Deloitte Huayong as the domestic audit institution and internal control audit institution in 2022, and Deloitte Hong Kong as the overseas audit institution in 2022. The situation of Deloitte Huayong and Deloitte Hong Kong is as follows:

(I) institutional information

1. Deloitte Huayong

(1) Basic information

The predecessor of Deloitte Touche Tohmatsu was Hujiang Deloitte certified public accountants Co., Ltd. established in February 1993. It was renamed Deloitte Touche Tohmatsu certified public accountants Co., Ltd. in 2002. In September 2012, it was approved by the Ministry of Finance and other departments to become a special general partnership. Deloitte Huayong's registered address is 30 / F, No. 222 Yan'an East Road, Huangpu District, Shanghai.

Deloitte Huayong has the practice certificate of accounting firm approved by the Ministry of finance, and is approved by the Ministry of Finance and China Securities Regulatory Commission to engage in the audit business of H-share enterprises. Deloitte Huayong has filed for securities service business in accordance with the administrative measures for the filing of accounting firms engaged in securities service business and other relevant documents issued by the Ministry of Finance and the CSRC. Deloitte Huayong has been engaged in Securities and futures related service business for more than 20 years and has rich experience in securities service business.

The chief partner of Deloitte Huayong is Mr. Fu Jianchao. At the end of 2021, there were 220 partners, 6681 employees and 1131 certified public accountants, including more than 220 certified public accountants who signed the audit report of securities service business.

Deloitte Huayong's total audited business income in 2020 was RMB 4 billion, including audit business income of RMB 3.1 billion and securities business income of RMB 688 million. Deloitte Huayong provided annual report audit services for 60 listed companies in 2020, with a total audit fee of RMB 205 million. Among the listed companies served by Deloitte Huayong, the main industries are manufacturing, finance, information transmission, software and information technology services, real estate and mining.

(2) Investor protection ability

The cumulative compensation limit of occupational insurance purchased by Deloitte Huayong exceeds 200 million yuan, which is in line with relevant regulations. Deloitte Huayong has not borne civil liability in relevant civil proceedings due to its practice in recent three years.

(3) Integrity record

Deloitte Huayong and its employees have not been subject to criminal punishment or administrative punishment due to their professional behavior in recent three years, and have not been subject to the supervision and management measures of securities regulatory institutions or the self-discipline supervision measures and disciplinary sanctions of stock exchanges, industry associations and other self-discipline organizations.

2. Deloitte Hong Kong

Deloitte Hong Kong is a partnership firm established in 1972 according to the laws of Hong Kong. It is wholly owned by its partners and provides audit services for many listed companies in Hong Kong, including banking, insurance, securities and other financial institutions. Deloitte Hong Kong is part of the Deloitte network.

Since October 1, 2019, Deloitte Hong Kong has been registered as an auditor of public interest entities under the Hong Kong Financial Reporting Bureau Ordinance. In addition, Deloitte Hong Kong obtained the temporary audit business license in China with the approval of the Ministry of finance, and is an accounting firm registered in uspcaob (American public company accounting oversight board), Canadian public accountability board (Canadian public responsibility board) and Japanese Financial Services Authority (Japanese financial agency) to engage in relevant audit business.

As of December 31, 2021, Deloitte Hong Kong has a total of about 2800 employees. Deloitte Hong Kong shall purchase sufficient occupational insurance every year in accordance with relevant laws and regulations.

The Hong Kong Institute of Certified Public Accountants conducts practice quality inspection on Deloitte Hong Kong every year. The practice quality inspection in the last three years has not found any matters that have a significant impact on the audit services provided by Deloitte Hong Kong.

(II) project member information

1. Basic information

Yu Yang, the project partner, is now a practicing member and senior member of the Chinese Institute of certified public accountants, a non practicing member of the American Institute of certified public accountants and the Australian Institute of public accountants. He is the certified public accountant signing the A-share audit report of the project. Yu Yang has been engaged in professional audit services for more than 20 years. He has worked full-time in the firm and has provided audit services for many large state-owned enterprises, listed companies and multinational enterprises. Yu Yang has been a partner for more than 10 years and has worked in securities business for more than 20 years. The audit reports of listed companies signed by Mr. Yu Yang in recent three years include Jiangsu Expressway Company Limited(600377) , Nanjing Chervon Auto Precision Technology Co.Ltd(603982) , Ways Electron Co.Ltd(605218) , Wuxi Apptec Co.Ltd(603259) . Mr. Yu Yang has provided professional audit services for Cansino Biologics Inc(688185) Jinyu Bio-Technology Co.Ltd(600201) company since 2021.

Mou Zhengfei, the quality control reviewer, is now a practicing member of Chinese certified public accountants and a member of the Hong Kong Institute of certified public accountants. Mr. Mou Zhengfei joined Deloitte Huayong since 1998 and registered as a Chinese certified public accountant in 2000. He worked full-time in the firm and provided audit services for many large state-owned enterprises, listed companies and multinational enterprises. Mou Zhengfei has been a partner for more than 13 years and has worked in securities business for more than 23 years. The audit reports of listed companies signed by Mou Zhengfei in recent three years include Adama Ltd(000553) . In addition, Mou Zhengfei served as the quality control reviewer of the audit of many listed companies, including Wuxi Apptec Co.Ltd(603259) . Mr. Mou Zhengfei has provided professional audit services for Cansino Biologics Inc(688185) Jinyu Bio-Technology Co.Ltd(600201) company since 2021.

Another certified public accountant signing the audit report of A-Shares of the project is Yang Jugu, who is now a practicing member of the China Institute of certified public accountants and a member of the Hong Kong Institute of certified public accountants. Yang Jugu has been engaged in professional audit services for more than 13 years. He has worked full-time in the firm and has provided audit services for many large state-owned enterprises, listed companies and multinational enterprises. Yang Jugu has been engaged in securities business for more than 9 years. Mr. Yang Jugu has provided professional audit services for Cansino Biologics Inc(688185) Jinyu Bio-Technology Co.Ltd(600201) company since 2021.

The certified public accountant signing the H-share audit report of the project is Chen Min, who is now a member of the Hong Kong Institute of certified public accountants and a non practicing member of the Australian Institute of certified public accountants. Chen Min has been engaged in professional audit services for nearly 20 years. He works full-time in the firm and has provided audit services for many large state-owned enterprises, listed companies and multinational enterprises. The audit reports of listed companies signed by Chen Min in recent three years include Hualing Pharmaceutical Technology (Shanghai) Co., Ltd., Weiya biotechnology holding group, Chaoyun Group Co., Ltd. and Zhongtong Express (Cayman) Co., Ltd. Mr. Chen Min has provided professional audit services for Cansino Biologics Inc(688185) Jinyu Bio-Technology Co.Ltd(600201) company since 2021.

2. Integrity record

In the past three years, the above personnel have not been subject to criminal punishment or administrative punishment due to their professional behavior, nor have they been subject to the supervision and management measures of securities regulatory institutions or the self-discipline supervision measures and disciplinary sanctions of stock exchanges, industry associations and other self-discipline organizations.

3. Independence

There are no circumstances that may affect the independence of Deloitte Huayong, Deloitte Hong Kong and above project partners, signed certified public accountants and project quality control reviewers.

(III) audit fees

The audit service fees of domestic and foreign audit institutions and internal control audit institutions in 2022 are determined according to the business responsibility, complexity, work requirements, required working conditions and working hours, as well as the professional knowledge and working experience invested by staff at all levels who actually participate in the business. The audit fee of the company's financial report in 2022 is RMB 3.6 million (excluding relevant taxes), of which the internal control audit fee is RMB 300000. 2、 Procedures to be performed by the accounting firm to be renewed

1. On March 21, 2022, the audit committee of the second board of directors of the company held its seventh meeting and agreed that the company would hire Deloitte Huayong as the domestic audit institution and internal control audit institution in 2022 and Deloitte Hong Kong as the overseas audit institution in 2022, and agreed to submit the proposal to the board of directors of the company for deliberation.

2. The independent directors of the company conducted pre audit on the employment of domestic and foreign audit institutions and internal control audit institutions and issued pre approval opinions:

All independent directors of the company believe that the company's renewal of Deloitte Huayong as the domestic audit institution and internal control audit institution in 2022 and Deloitte Hong Kong as the overseas audit institution in 2022 meet the actual situation of the company and the needs of annual audit work. Deloitte Huayong and Deloitte Hong Kong have sufficient independence, professional ability of audit services and investor protection ability, and are competent for the annual audit of the company. Therefore, we approved the proposal on hiring domestic and foreign audit institutions and internal control audit institutions in 2022 in advance and agreed that the company would submit the proposal to the eighth meeting of the second board of directors for deliberation.

3. The independent directors of the company expressed independent opinions on the employment of domestic and foreign audit institutions and internal control audit institutions:

The company plans to continue to employ Deloitte Huayong as the domestic audit institution and internal control audit institution in 2022 and Deloitte Hong Kong as the overseas audit institution in 2022, which meets the actual situation of the company and the needs of annual audit work. Deloitte Huayong and Deloitte Hong Kong have sufficient independence, professional ability of audit services and investor protection ability, and are competent for the company's annual audit. The company's continued employment of the above audit institutions complies with the provisions of relevant laws, administrative regulations and the articles of association, which is conducive to ensuring the quality of the company's audit work and does not damage the interests of the company and all shareholders.

Therefore, we agree to the proposal on hiring domestic and foreign audit institutions and internal control audit institutions in 2022 and agree to submit the proposal to the general meeting of shareholders for deliberation.

4. On March 25, 2022, the company held the 8th meeting of the second board of directors. The meeting deliberated and approved the proposal on hiring domestic and foreign audit institutions and internal control audit institutions in 2022, agreed that the company would continue to hire Deloitte Huayong as the domestic audit institution and internal control audit institution in 2022, Deloitte Hong Kong as the overseas audit institution in 2022, and agreed to submit the proposal to the general meeting of shareholders of the company for deliberation.

5. On March 25, 2022, the company held the 11th meeting of the second board of supervisors, deliberated and approved the proposal on hiring domestic and foreign audit institutions and internal control audit institutions in 2022, and agreed that the company would continue to hire Deloitte Huayong as the domestic audit institution and internal control audit institution in 2022, and Deloitte Hong Kong as the overseas audit institution in 2022.

6. The employment of domestic and foreign audit institutions and internal control audit institutions needs to be submitted to the general meeting of shareholders of the company for deliberation, which will take effect from the date of deliberation and approval by the general meeting of shareholders of the company.

It is hereby announced.

Cansino Biologics Inc(688185) Jinyu Bio-Technology Co.Ltd(600201) board of directors March 28, 2022

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