Key investment points:
Omicron is rampant all over the world and builds a defense line by multiple means: Omicron has replaced delta strain and become the main strain of global epidemic, with high infectivity and relatively low toxicity as its main characteristics; At present, China still adopts the “dynamic clearing” policy. The recent severe situation of epidemic prevention and control in Hong Kong has put great pressure on the prevention and control in the mainland. In the face of such an epidemic, vaccines, testing, neutralizing antibodies, small molecule drugs, traditional Chinese medicine and other means coexist to build a wall for epidemic prevention and control in the post epidemic era.
“Integrated Chinese and Western” therapeutic drugs will become the main means of epidemic prevention and control in China. Since the outbreak of the epidemic, clinical doctors outside China have been exploring the therapeutic effects of new and old antiviral drugs. From the early clinical reference of redcivir and a variety of neutralizing antibodies to the emergence of molnupiravir of Merck and paxlovid small molecule oral drugs of Pfizer, covid-19 therapeutic drugs have gradually developed into more efficient and convenient varieties. Based on the treatment of Western medicine in China, more treatment schemes of traditional Chinese medicine have been explored. The “three drugs and three prescriptions” represented by Lianhua Qingwen capsule has been clinically proved to have obvious therapeutic effect, shine brightly in the process of anti epidemic, and will not be absent from the prevention and control of covid-19 in China in the future. China will continue to implement the mainstream scheme of “integration of Chinese and Western medicine” in the future. It is expected to successfully develop more domestic small molecule specific drugs in the future. The combination of specific drugs with traditional Chinese medicine will become a unique and important “Chinese scheme” for China’s anti epidemic. Pfizer’s small molecule drug industry chain and domestic small molecule drug field, focusing on: Porton Pharma Solutions Ltd(300363) , Asymchem Laboratories (Tianjin) Co.Ltd(002821) , Wuxi Apptec Co.Ltd(603259) , Shanghai Junshi Biosciences Co.Ltd(688180) , Xiansheng pharmaceutical, etc; In the field of anti epidemic of traditional Chinese medicine, it is suggested to focus on: Shijiazhuang Yiling Pharmaceutical Co.Ltd(002603) , Shandong Buchang Pharmaceuticals Co.Ltd(603858) , Tianjin Chase Sun Pharmaceutical Co.Ltd(300026) , Chinese traditional medicine, Zhangzhou Pientzehuang Pharmaceutical Co.Ltd(600436) , etc.
There are great differences in covid-19 detection between China and foreign countries, and antigen detection has a great opportunity for breeding in the future. At present, there are many covid-19 virus detection methods, including nucleic acid detection, antibody detection and antigen detection. Overseas mainly focuses on antigen detection, and China mainly focuses on nucleic acid detection. At present, nucleic acid detection is still the main covid-19 virus detection method in China, but with the global epidemic entering a relatively stable stage, China is expected to gradually open its door in the future. Antigen self-test is expected to become one of the supplementary detection methods for covid-19 prevention and control due to its price, convenience and other characteristics. It is suggested to focus on: Zhejiang Orient Gene Biotech Co.Ltd(688298) , an Xu biology, Hangzhou Biotest Biotech Co.Ltd(688767) Beijing Strong Biotechnologies Inc(300406) , Guangzhou Wondfo Biotech Co.Ltd(300482) etc.
Vaccine to build a national basic immune barrier, strengthen needle or sequential vaccination is in progress. The vaccine has built a basic immune barrier in mainstream countries and regions, which is the basis for the global common defense against the epidemic. With the approval of the joint prevention and control mechanism of the State Council, the National Health Commission began to deploy sequential immunization. After the implementation of the sequential booster immunization strategy, the target population who has completed the whole process of vaccination with three kinds of inactivated vaccines can also choose the recombinant protein vaccine of zhifeilongke horse or Cansino Biologics Inc(688185) of adenovirus vector vaccine for sequential booster immunization. In the post epidemic era, we are optimistic about the overseas vaccine market and China’s enhanced injection or sequential vaccination market. It is suggested to focus on: Chongqing Zhifei Biological Products Co.Ltd(300122) , kangxinuo, Shenzhen Kangtai Biological Products Co.Ltd(300601) , etc.
Risk tips: risk of sharp price reduction of products, risk of drug R & D failure, covid-19 virus mutation, etc.
