Youningwei: letter of recommendation from Minsheng Securities Co., Ltd. on the company’s initial public offering and listing on the gem

Minsheng Securities Co., Ltd

about

Shanghai Youning Weisheng Technology Co., Ltd. made an initial public offering and was listed on the gem

of

Listing recommendation

Sponsor (lead underwriter)

(No. 8, Puming Road, China (Shanghai) pilot Free Trade Zone)

December, 2001

Shenzhen Stock Exchange:

Shanghai Youning Weisheng Technology Co., Ltd. (hereinafter referred to as the “issuer”, “company” or “youningwei”) intends to apply for initial public offering and listing on the gem (hereinafter referred to as the “issuance”), and has hired Minsheng Securities Co., Ltd. (hereinafter referred to as “Minsheng securities”, “sponsor” and “the institution”) )As the sponsor of this offering.

Minsheng securities and its sponsor representatives have, in accordance with the company law of the people’s Republic of China (hereinafter referred to as the “company law”), the securities law of the people’s Republic of China (hereinafter referred to as the “Securities Law”), and the measures for the administration of the registration of initial public offerings on the gem (for Trial Implementation) (hereinafter referred to as the “measures for the administration of registration”) Relevant laws and administrative regulations such as Shenzhen Stock Exchange GEM Listing Rules (revised in December 2020), measures for the administration of securities issuance and listing recommendation business, and China Securities Regulatory Commission (hereinafter referred to as “CSRC”) )I. in accordance with the provisions of Shenzhen Stock Exchange, be honest, trustworthy, diligent and responsible, issue this listing recommendation letter in strict accordance with the business rules, industry practice norms and ethical standards formulated according to law, and ensure the authenticity, accuracy and integrity of the documents issued.

Unless otherwise specified in this listing recommendation letter, relevant terms have the same meaning as in the prospectus of Shanghai Youning Weisheng Technology Co., Ltd. for initial public offering and listing on GEM.

catalogue

Section 1 basic information of the issuer three

1、 Basic information of the issuer three

2、 The issuer’s main business, core technology and R & D level three

3、 Main operating and financial data and indicators ten

4、 Main risks of the issuer Section II basic information of this offering sixteen

1、 Overview of this offering sixteen

2、 Introduction to the sponsor, sponsor representative and project team members seventeen

3、 Whether the sponsor has any description that may affect the fair performance of its duties Section III commitments of the sponsor Section IV recommendation on this securities offering twenty

1、 The issuer’s decision-making procedures on this securities issuance twenty

2、 The issuer meets the issuance conditions specified in Article 12 of the securities law III. The issuer complies with the provisions of the measures for the administration of the registration of initial public offerings on the gem (for Trial Implementation)

Terms of issue 4. The issuer complies with Article 2.1 of the Shenzhen Stock Exchange GEM Listing Rules 1. Required issuance

Conditions Section V continuous supervision work arrangement twenty-five

Section 1 basic information of the issuer

1、 Basic information of the issuer

Company name: Shanghai Youning Weisheng Technology Co., Ltd

English Name: Shanghai Universal biotech Co., Ltd

The registered capital is 65 million yuan

Legal representative: Leng Zhaowu

Date of establishment of the company: October 22, 2004

Date of establishment of the joint stock company: December 8, 2015

Address: room 1505, No. 1690, Kongjiang Road, Yangpu District, Shanghai

Postal Code: 200082

Tel: 021-38939000

Fax 021-38015116

Internet address http://www.univ-bio.com.

mailbox ir@univ -bio. com.

The Department responsible for information disclosure and investor relations of the office of the board of directors

Department head Qi Yanfang

Tel: 021-38939097

2、 Main business, core technology and R & D level of the issuer (I) main business of the issuer

The company is an agent providing antibody Centered Life Science reagents and related instruments, consumables and comprehensive technical services for colleges and universities, scientific research institutes, hospitals and biomedical enterprises.

The company focuses on life science research services. According to the characteristics of a wide variety of life science reagents, limited variety of single brand products, large customer group and scattered application fields, the company has built a professional and comprehensive one-stop platform for life science comprehensive services in China. The company integrates Agilent, BD, CST Cytiva (formerly GE), Merck, PerkinElmer, R & D systems, Miltenyi, MSD, Qiagen and other more than 50 well-known brand antibody products in the industry have formed a supply system dominated by third-party brand products and supplemented by independent brand products, and established a “youningwei antibody expert” in the industry Brand image. At present, the company provides more than 4.69 million kinds of life science reagent products SKU, covering research objects at different levels such as genes, proteins, cells, tissues and animals, covering basic research of life science, basic research of medicine, in vitro diagnostic research, drug research and development, cell therapy research and other fields. It is one of the most comprehensive suppliers of antibody varieties and specifications in China, Effectively meet the diversified application needs of researchers in different fields. On the basis of life science reagents, the company provides relevant instruments and consumables to fully meet the scientific research needs of customers.

The life science experiment process is complex and the products and technology are highly professional. While providing reagents, instruments and consumables, the company provides comprehensive technical services for scientific researchers, which strongly supports the sales of the company’s products. The company’s experimental outsourcing service can improve the experimental efficiency of customers and reduce the experimental cost; Technical support services cover the whole process of sales. Based on the understanding of customers’ needs, pre-sales engineers provide them with professional consultation such as product selection, combination and experimental scheme design, customize antibodies according to customers’ special needs, and provide technical training combined with Wuxi Online Offline Communication Information Technology Co.Ltd(300959) ; The company’s intelligent supply chain system realizes the effective control of the ambient temperature of goods distribution and the whole process tracking of orders, which is convenient for customers to manage the experimental plan; In addition, the company provides customers with guidance on reagent use, instrument calibration and computer operation, assists customers in experimental data processing and result analysis, establishes experimental standard operating procedures (SOP), and provides customers with one-stop platform services for procurement and comprehensive technical support.

With comprehensive life science research products, comprehensive technical support, one-stop platform service and good brand image, the company has accumulated a wide range of high-quality customer groups. From 2017 to January to June 2021, the company’s total business orders exceeded 530000, The company has served more than 9700 customers (covering more than 100000 scientific researchers), and the company’s own e-commerce platform has more than 92200 registered users. The company’s customers include Tsinghua University, Peking University, Fudan University, Shanghai Jiaotong University, Zhejiang University and other colleges and universities (covering 92 985 and 211 universities); scientific research institutes such as the system of the Chinese Academy of Sciences, the system of the Chinese Academy of Medical Sciences and the system of the Chinese Academy of Agricultural Sciences (covering 454 scientific research institutes); Zhongshan Hospital Affiliated to Fudan University, the First Affiliated Hospital of China Medical University, Union Hospital Affiliated to Huazhong University of science and technology, the Ninth People’s Hospital Affiliated to Shanghai Jiaotong University, etc (covering 498 class III hospitals); and biomedical enterprises such as Tellgen Corporation(300642) (300642. SZ), Pharmaron Beijing Co.Ltd(300759) (300759. SZ / 03759. HK), Wuxi Apptec Co.Ltd(603259) (603259. SH / 02359. HK), Jiangsu Hengrui Medicine Co.Ltd(600276) (600276. SH) (covering more than 50 listed companies outside China).

(2) Core technology

As of the issuance date of this listing recommendation letter, the main core technologies owned by the company are as follows:

(1) Product category

S / N core technology name application product / technology description technology maturity field source

A specific antibody coated ELISA reagent coated the antibody to the solid-phase carrier 96 well plate

1 technology kit, so as to realize the pre development scale of ELISA kit and apply the coating board.

The designed antigenic polypeptide fragment was used for experimental autonomy

2 traditional antibody preparation technology antibody customization after multiple immunization with rabbits, blood was collected, and polyclonal antibody was purified and isolated from blood R & D scale application serum.

A myeloma that can grow and reproduce indefinitely

3 preparation of mouse monoclonal antibody mouse monoclonal antibody, cell, cell independent small batch trial production with mouse immune spleen cells, customized fusion of antibody preparation technology, screening of monoclonal cells, and finally research and development

Mouse monoclonal antibody production.

S / N core technology name application product / technology description technology maturity field source

Proa / prog was formed by inverse suspension method and chemical crosslinking method

Magnetic beads and magnetic microspheres for purifying antibodies, and then through chemical modification technology

4preparation of proa / prog magnetic beads IP / co-Ip inspection, coupling proa / prog on the surface of microspheres, developing small batch pilot production technology test agent box, so as to prepare proa / prog magnetic beads

It can be used to isolate and purify antibodies.

By inverse suspension method and chemical crosslinking method

The labeled antibody used to purify protein is magnetically formed into magnetic microspheres, which are independently modified by chemical modification technology

The preparation technology of antibody magnetic beads is bead technology. The labeled antibody is coupled on the surface of microspheres, and the labeled antibody magnetic beads are prepared from R & D and small batch trial production. The magnetic beads can be used

The protein was isolated and purified.

(2) Service class

S / N core technology name application product / technology description technology domain source

According to the multi-dimensional attribute parameters set by the customer (such as antigen of antibody)

Target, source host, reaction species, application method, marker

1) accurate testing of reagent products (such as the status of reagent products), combined with the product evaluation and independent technical price recommendation indicators preset in the self owned database of the online platform (such as fluorescein emission spectrum, brand service quality, R & D logistics speed, etc.), the development of reagent products is realized through logical algorithm

Accurate retrieval.

According to the selection technology of independent 2 reagent products such as experimental methods, experimental processes and sample types, the online platform presets multi-dimensional options for customers to choose, and realizes the accurate retrieval of reagent products through layer by layer decomposition, R & D and data matching algorithms.

 

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