600645: Vcanbio Cell & Gene Engineering Corp.Ltd(600645) independent opinions of independent directors on adjusting the remuneration of senior managers

Annex 4:

Vcanbio Cell & Gene Engineering Corp.Ltd(600645)

Independent opinions of independent directors on adjusting the remuneration of senior managers

In accordance with the rules for independent directors of listed companies, the guidelines for the governance of listed companies, the rules for the listing of shares on the Shanghai Stock Exchange, the articles of association and other relevant provisions of the CSRC, as an independent director of the company, based on independent judgment, The independent opinions on the proposal on adjusting the remuneration of senior managers considered and adopted at the 14th extraordinary meeting of the 10th board of directors are as follows:

The company's salary adjustment of senior managers is based on the industry and scale of the company, combined with the actual operation of the company, which helps to mobilize the enthusiasm and creativity of senior managers, does not harm the interests of the company and shareholders, and complies with relevant national laws, regulations and the articles of Association. In view of this, we agree to adjust the remuneration of senior managers this time.

independent director:

Chen Min, Pei duanqing

Hou Xinyi

February 18, 2002

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