Recently, the Department of Neurology of the high tech Zone of the First Affiliated Hospital of Anhui Medical University successfully treated two adult patients with spinal muscular atrophy (SMA) type III with intrathecal injection of nosinasheng sodium injection. This is the first batch of adult patients in Anhui Province to benefit after the drug was officially included in the implementation of medical insurance.
"Every small group should not be abandoned." On December 3, 2021, the national medical insurance administration announced the adjustment results of the medical insurance drug catalogue in 2021, adding a total of 74 drugs into the catalogue, which will be implemented on January 1, 2022. The price of nosinasheng sodium injection, known as the "sky high life-saving drug", has been reduced from 700000 yuan / needle to 33000 yuan / needle through the "soul bargaining" of the National Medical Insurance Bureau, which brings hope to patients with spinal muscular atrophy (SMA).
Mr. Yan of Bengbu is 35 years old and works in school; Mr. Xu, 30, who lives in Hefei, is an it practitioner. Both of them are genetically diagnosed SMA patients with weak limbs, different walking posture from ordinary people, and it is also very difficult to climb stairs. The diagnosis has been made for 6 years, but the drug has not been treated in the past due to economic reasons. In late January, they were admitted to the Department of Neurology in the high tech Zone of the First Affiliated Hospital of Anyi University. The medical staff formulated a sound and reasonable individualized evaluation and administration plan in combination with the specific condition of the patient, and straightened out the dual channel drug purchase route of drugs. On January 27, Mr. Yan and Mr. Xu successfully received intrathecal injection of sodium nosinogenase.
At present, the two patients are in good condition and have been discharged from the hospital on January 28. It is planned to receive a second injection in two years.
Only 5ml of sodium nosinogenase injection. Since the drug needs special transportation equipment for constant temperature transportation, the pharmacist will accompany the whole process of sheath injection. According to the drug instructions, intrathecal injection is required, that is, the drug is directly injected into the subarachnoid space through lumbar puncture, so that the drug is dispersed in cerebrospinal fluid and acts directly on nerve cells. According to Chen Xianwen, chief physician of the Department of Neurology in the high tech Zone of the First Affiliated Hospital of Anyi University, during the puncture, the puncture is generally performed between the L3 and L4 segments of the lumbar spine, and 5ml cerebrospinal fluid is extracted first. Then, take out the medicine from the incubator and put it in your hand to warm and thaw it to room temperature; Another 5 ml of the drug was injected very slowly in a few minutes. SMA patients need lifelong injection of sodium nosinogenase. Through the follow-up continuous medication, it is expected to stabilize and improve the motor function of patients.
