Monkeypox cases found in many countries! Concept stocks rose in response, and enterprise testing products received orders!

In early Monday trading, the three major A-share indexes opened high and went low, and the gem index once fell more than 1%. As of midday closing, the Shanghai index fell 0.47%, the Shenzhen composite index fell 0.71% and the gem index fell 0.76%.

On the disk, the performance of large consumer sectors such as household appliances, food and beverage was poor; Steel, nonferrous metals and other cyclical resource stocks broke out against the trend; Boosted by favorable policies, the agriculture, forestry, animal husbandry and fishery sector also increased compared with the previous one. Overall, the theme ticket is relatively active, and the heavyweights are generally adjusted.

In addition, the most concerned concept on the disk recently is “monkeypox concept stock”. During the weekend, the monkeypox epidemic continued to ferment, driving the rise of monkeypox concept stocks in early trading, and covid-19 detection and other pharmaceutical related sectors followed suit.

monkeypox stocks rose sharply at the opening

Monkeypox outbreak continues to ferment!

According to who data on the 21st, since May 13, 92 confirmed cases and 28 suspected cases have been reported in 12 countries without monkeypox virus in three who regional offices.

Affected by the news of the discovery of monkeypox cases in many countries, many monkeypox concept stocks rose sharply this morning.

Shanghai Zj Bio-Tech Co.Ltd(688317) call auction stage harvest 20% limit, as of noon closing, the stock still rose more than 16% Sansure Biotech Inc(688289) increased by about 14%, and Daan Gene Co.Ltd(002030) increased by more than 8%.

In fact, with the rise in the popularity of monkeypox virus, the speculation of funds on related concepts began last week Shanghai Zj Bio-Tech Co.Ltd(688317) rose by more than 16% on Friday, and vaccine concept stocks such as Changchun High And New Technology Industries (Group) Inc(000661) , Liaoning Chengda Biotechnology Co.Ltd(688739) performed well.

Some institutions believe that monkeypox cases are found in many countries, and there may be theme investment opportunities for short-term relevant testing reagent companies.

For example, Shanghai Zj Bio-Tech Co.Ltd(688317) released a message on the official wechat that the company’s monkeypox virus nucleic acid detection reagent can accurately identify monkeypox virus Shanghai Zj Bio-Tech Co.Ltd(688317) existing CE registered product – monkeypox virus nucleic acid determination kit (fluorescence PCR method), which can accurately identify monkeypox virus and help the accurate diagnosis and prevention and control of related diseases by determining the gene fragment of monkeypox virus by specific fluorescence method.

The company’s new nucleic acid detection kit for monkeypox virus has been released on May 22, relying on the company’s experience in rapid detection of monkeypox virus and CO89 nucleic acid fragment, which can be used to identify all kinds of monkeypox virus.

Jiangsu Bioperfectus Technologies Co.Ltd(688399) official website shows that the company has monkeypox virus nucleic acid detection kit (fluorescent PCR method), with the article number of jc70115, but this product has not obtained the registration certificate at present.

US stocks’ monkeypox concept also rose

On May 21, according to foreign media reports, after the United States reported the first case of human infection with monkeypox virus this year, the U.S. health department has ordered millions of doses of monkeypox vaccine worth 119 million US dollars.

And, because smallpox vaccine can provide some effectiveness in preventing monkeypox, this statement supports the stock price performance of pharmaceutical companies focusing on smallpox virus vaccines and treatments.

Last week, pharmaceutical companies SIgA technologies (SIgA. US) and chimerix (cmrx. US) rose 68% and 41% respectively, while vaccine manufacturers emergency biosolutions (EBs. US) and Bavarian Nordic (bvnry. US) rose 23% and 79% respectively.

In addition, smallpox vaccine developer tonix pharmaceuticals (tnxp. US) also increased slightly by 32% in the last two trading days of last week due to the increase of monkeypox cases.

who:

more countries may find monkeypox cases

On the news, the World Health Organization issued an early warning of monkeypox outbreak on May 21, saying that in view of the fact that cases have been found in many countries where monkeypox virus is not prevalent, more cases may be found in these countries and other countries in the future, and monkeypox virus will spread further.

According to who data on the 21st, since May 13, 92 confirmed cases and 28 suspected cases have been reported in 12 countries without monkeypox virus in three who regional offices, and there have been no deaths so far. Among them, the confirmed and suspected cases are mainly from the UK, Spain and Portugal, and the rest are distributed in Australia, Belgium, Canada, France, Germany, Italy, the Netherlands, Sweden and the United States.

The who said there was no clear travel history of monkeypox endemic areas in these cases. So far, all cases confirmed by PCR have been identified as the evolutionary branch of West Africa infected with the virus. The genome sequence of swab samples from confirmed cases in Portugal shows that the monkeypox virus leading to the current epidemic closely matches the cases exported from Nigeria to the UK, Israel and Singapore in 2018 and 2019.

Who expects that with the expansion of surveillance, more cases may be found in countries that have reported cases and other countries in the future. The current response focuses on providing accurate information to the people most vulnerable to monkeypox to prevent further transmission. Evidence suggests that the highest risk of infection is among people who have had close physical contact with monkeypox patients after they developed symptoms.

Monkeypox cases often occur in West and Central Africa, but the confirmed and suspected cases reported by many countries do not have any travel history in monkeypox endemic areas, which is not normal. Therefore, who believes that there is an urgent need to raise awareness of monkeypox and take comprehensive measures to timely detect and isolate cases, track contacts and provide supportive care to limit further transmission.

The threat of covid-19 virus has not been completely eliminated. Monkeypox, which is considered to have the greatest impact on public health since the eradication of smallpox, is sweeping in.

In this regard, experts described the epidemic as “unusual”, because the interpersonal transmission of monkeypox was previously considered extremely rare.

Monkeypox is a rare disease outside central and West African countries. Recently, it has become a news hotspot in less than half a month. Cases have been found in Britain, Spain, Portugal, the United States, Sweden, Italy and Canada.

(from 13:00 on May 13 to 21, 2022, non endemic countries reported cases of monkeypox to who)

(geographical distribution of confirmed and suspected cases of non endemic monkeypox as of 13:00 on May 13-21, 2022)

The who said that early cases were unusual for three reasons: with one exception, none of them had a relevant travel history to monkeypox endemic areas; Most cases are found in sexual health services and men who have sex with men, and the wide distribution across many countries in Europe suggests that transmission may have been going on for some time.

The WHO warns that more cases are expected in more countries in the coming weeks.

monkeypox originated from monkeys

According to the introduction of “Huashan infection”, monkeypox virus and smallpox virus are close relatives. Both of them are orthopox virus. Orthopox virus also includes vaccinia virus, cowpox virus and several other animal related pox viruses.

The name “monkeypox” comes from monkeys, but in fact, monkeys are not the reservoir host of monkeypox virus. Similar to humans, monkeys are only accidental hosts of monkeypox virus.

In nature, many animal species have been found to be infected with monkeypox virus. Some evidence suggests that indigenous rodents in Africa, such as the Gambian giant mouse (Cricetomys gambianus) and squirrel, may be the reservoir hosts of the virus.

epidemic situation occurs interpersonal transmission

As countries increase surveillance efforts, more and more countries have reported cases of the virus. On the 21st local time, who said again, “available information shows that interpersonal transmission is occurring among people in close physical contact with symptomatic cases.”

what does close physical contact include

It is understood that close contact with infected people – respiratory secretions, skin damage sites and contaminated items may be infected with monkeypox. Monkeypox can also be transmitted sexually from mother to child.

what are the possible symptoms of monkeypox infection

It is reported that the incubation period of the disease (from exposure to onset) is 5 to 21 days. Infected people initially develop mild flu like diseases – headaches, fever, rashes and swollen lymph nodes. A rash will appear after a few days, usually starting from the face. The rash usually spreads to other parts of the body, mainly the limbs. The palms and soles of the feet are often affected.

Unlike other rashes, it usually includes blisters formed on the palm of the hand. Scar lesions will form in the next stage of the disease and can last two to six weeks. For most people, monkeypox is a self limiting disease that usually lasts two to four weeks and recovers completely.

monkeypox virus how to control it

According to “Huashan infection”, monkeypox and smallpox are close relatives. Their genomic structures are very similar, and they also have many similarities in biological characteristics and pathogenicity. At present, although there is no specific treatment, the vaccine against smallpox virus also has protective effect on monkeypox virus. The effect of smallpox vaccine on the prevention of “monkeypox” is about 85%.

how to identify monkeypox virus

After the monkeypox virus spread in many countries, many listed companies opened the reserve of monkeypox virus detection kits.

Sansure Biotech Inc(688289) it was announced on May 22 that the company has reserved monkeypox virus nucleic acid detection kit (PCR fluorescent probe method) in its scientific research products, which can quickly identify monkeypox virus by specifically detecting the nucleic acid fragment of monkeypox virus. The reagent has the characteristics of high sensitivity and simple operation. It is suitable for rapid diagnosis of related diseases caused by monkeypox virus infection. It is compatible with fluorescent PCR platform and Sansure Biotech Inc(688289) poct platform. It can be quickly applied to the established covid-19 nucleic acid detection platform Sansure Biotech Inc(688289) covid-19 related products have served more than 160 countries and regions around the world, helping the nucleic acid detection capacity of tens of thousands of laboratories outside China grow from scratch or several times to tens of times. Based on these powerful covid-19 nucleic acid detection capabilities, it can help laboratories in various countries carry out monkeypox virus nucleic acid detection efficiently and help the rapid diagnosis, prevention and control of monkeypox. At present, the company is actively promoting the overseas registration of the product.

Shanghai Zj Bio-Tech Co.Ltd(688317) indicates that the company’s existing CE registered product – monkeypox virus nucleic acid assay kit (fluorescence PCR method). The gene fragment of monkeypox virus is determined by specific fluorescence method, which can accurately identify monkeypox virus and help the accurate diagnosis, prevention and control of related diseases. The reagent is easy to operate and can be matched with Shanghai Zj Bio-Tech Co.Ltd(688317) austramic automatic nucleic acid detection platform to automatically complete the rapid and automatic diagnosis of monkeypox virus.

The company also revealed on the interactive platform that the monkeypox virus nucleic acid determination kit (fluorescence PCR method) developed by the company has obtained the EU CE certification. At present, the kit has small batch orders from outside China.

Jiangsu Bioperfectus Technologies Co.Ltd(688399) official website shows that the company has monkeypox virus nucleic acid detection kit (fluorescent PCR method), Article No. jc70115, but this product has not obtained the registration certificate at present.

ST Kehua 5 on the investor interaction platform on May 21, said that recently, many overseas countries have reported monkeypox cases one after another. The company has organized R & D personnel for the first time to develop and complete the technical reserve of monkeypox virus nucleic acid detection kit (PCR fluorescent probe method). The kit can detect the nucleic acid fragment of monkeypox virus specifically, so as to quickly identify monkeypox virus. These kits can be used by disease control, scientific research institutions and laboratories.

Daan Gene Co.Ltd(002030) said that the company has a reserve of monkeypox virus related scientific research products, but there is no relevant certified reagent at present.

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