Since the first case of monkeypox was first confirmed in Britain on May 6 this year, monkeypox virus has spread to more than 10 countries such as the United States, Canada and Australia. According to the who, the mortality of some monkeypox viruses may reach 10%.
At present, Sansure Biotech Inc(688289) , Daan Gene Co.Ltd(002030) and other listed companies have announced that they have reserved monkeypox virus nucleic acid detection kits. At the same time, “monkeypox concept stocks” changed on Friday, and Shanghai Zj Bio-Tech Co.Ltd(688317) once impacted the “20cm” trading board.
US purchases millions of vaccines
According to the World Health Organization, as of May 21, 92 confirmed cases and 28 suspected cases of monkeypox had been reported in 12 non monkeypox endemic countries. At the same time, the WHO warned that monkeypox virus has been secretly transmitted in the community, and the number of infections may further increase in the future.
It is worth noting that the mortality of some monkeypox viruses is high, and there is no specific treatment for the time being. According to who, monkeypox virus is divided into West African evolutionary branch and Congo Basin evolutionary branch. Among them, the mortality of monkeypox virus in West Africa branch is low, about 1%, while the mortality of Congo Basin branch may be as high as 10%.
According to the who, monkeypox virus infection symptoms are similar to smallpox, but the clinical severity is mild. The incubation period is usually 6 to 13 days and may be as long as 21 days initial symptoms include fever, headache, enlarged lymph nodes, muscle soreness and severe fatigue. Enlarged lymph nodes help to distinguish monkeypox from smallpox. After a few days of fever, it develops into a large-area rash on the face and other parts of the body, which may lead to secondary infection, bronchopneumonia, sepsis, etc.
Who data show that the effective rate of smallpox vaccine against monkeypox virus has reached 85%.
On May 21, according to media reports, after the United States reported the first case of human infection with monkeypox virus this year, the U.S. health department has ordered millions of doses of monkeypox vaccine worth 119 million US dollars.
viral zoonosis
What is monkeypox virus? Where does it come from?
Public information shows that monkeypox is a viral zoonosis, and its pathogen monkeypox virus is a DNA (deoxyribonucleic acid) virus, belonging to the genus poxvirus of poxviridae, which is “close relative” to the smallpox virus that has been raging for thousands of years in human history. Monkeypox virus was first discovered in 1958. At that time, a group of monkeys used for research had a “pox like” infectious disease, so it was named. Since the World Health Organization announced the complete elimination of smallpox in 1980, monkeypox virus has become the normal pox virus with the greatest impact on public health.
Although monkeypox virus was first confirmed in monkeys, rodents are most likely to be its natural host, according to updated information on the WHO website on the 19th. In Africa, it has been found that animals such as squirrels, Gambian rats and different kinds of monkeys may be infected with monkeypox virus.
In 1970, the first human case of monkeypox infection was found in the Democratic Republic of the Congo. Subsequently, monkeypox virus appeared in other parts of the African continent. In 2003, the first monkeypox epidemic outside the African continent occurred in the United States, with dozens of people infected. The source of infection can be traced back to Gambian rats and dormouses transported from Ghana to the United States.
Direct contact with the blood, body fluid, skin or mucous membrane damaged parts of infected animals may cause monkeypox virus to spread from animals to humans. Eating improperly cooked infected animals is also a risk factor for “animal to human” generally speaking, monkeypox virus is not commonly transmitted between people. Interpersonal transmission routes include close contact with respiratory secretions, skin damaged parts or contaminated items of infected persons. It usually takes a longer time to spread respiratory droplets face to face. In addition, monkeypox virus may be transmitted from mother to child through placenta or close contact during childbirth
Who stressed that in order to reduce the risk of infection, in areas where monkeypox virus is prevalent, contact with wild animals should be avoided, especially unprotected contact with the meat, blood or other parts of sick or dead animals. Edible meat must be thoroughly cooked.
has reserved monkeypox Test Kit
After the spread of monkeypox virus in many countries around the world, many listed companies have opened the reserve of monkeypox virus detection kits.
On May 22, Sansure Biotech Inc(688289) announced through official wechat that monkeypox virus nucleic acid detection kit (PCR fluorescent probe method) has been reserved in the company’s scientific research products, which is suitable for rapid diagnosis of related diseases caused by monkeypox virus infection. It is compatible with fluorescent PCR platform and Sansure Biotech Inc(688289) POCT platform, and can be quickly applied to the established covid-19 nucleic acid detection platform.
Image source: Sansure Biotech Inc(688289) wechat official account
At the same time, Sansure Biotech Inc(688289) relevant person in charge introduced that Shengxiang’s monkeypox reagent can be detected in 8 minutes on POCT instrument and 96 samples can be detected in 30 minutes on conventional PCR instrument. At present, the company is actively promoting the overseas registration of the product.
In addition, Jiangsu Bioperfectus Technologies Co.Ltd(688399) official website shows that the company has monkeypox virus nucleic acid detection kit (fluorescent PCR method) with article number jc70115, but this product has not obtained registration certificate at present Daan Gene Co.Ltd(002030) also said on the interactive platform that the company has reserves of monkeypox virus related scientific research products, but there is no relevant certified reagent at present.
However, the relevant person in charge of a biopharmaceutical company said: “at present, there is no commercial monkeypox detection kit in China. The companies announced now are all technical reserves, which are supplied to disease control departments or laboratories. If they want to be commercial, there is still a process to go. But if they need to be commercial, this process is also very fast.”
On the A-share market, “monkeypox concept stock” changed on Friday. On May 20, Shanghai Zj Bio-Tech Co.Ltd(688317) once hit the daily limit, and Daan Gene Co.Ltd(002030) , ST Kehua, Jiangsu Bioperfectus Technologies Co.Ltd(688399) and other detection and diagnosis stocks also rose sharply.
Recently, an investor asked Shanghai Zj Bio-Tech Co.Ltd(688317) on the SSE e interactive platform: does the company have a monkeypox virus nucleic acid assay kit (fluorescence PCR method)? Has the kit passed the EU CE certification?
On the evening of May 22, according to Shanghai Zj Bio-Tech Co.Ltd(688317) official wechat, Shanghai Zj Bio-Tech Co.Ltd(688317) existing CE registered product – monkeypox virus nucleic acid assay kit (fluorescence PCR method). The gene fragment of monkeypox virus is determined by specific fluorescence method, which can accurately identify monkeypox virus and help the accurate diagnosis, prevention and control of related diseases. The reagent is easy to operate and can be matched with Shanghai Zj Bio-Tech Co.Ltd(688317) austramic automatic nucleic acid detection platform to automatically complete the rapid and automatic diagnosis of monkeypox virus.
\u3000\u3000
