Monkeypox virus continues to receive global attention!
The first case was found in Britain on May 7, and now it has been found in at least 11 countries – the United States, Canada, Australia, the United Kingdom, France, Belgium, Sweden, Spain, Portugal, Germany, Italy , the case has been confirmed and has spread , at present, 80 cases of monkeypox have been confirmed worldwide, and another 50 cases are suspected P align = “center” distribution map of monkeypox in Europe and America as of May 19 p align = “center” source: Huashan infection
“at present, the source of infection of these cases has not been confirmed” . For the monkeypox epidemic in various countries, the World Health Organization confirmed to hold an emergency meeting on monkeypox on the same day on the 20th local time.
according to the who, monkeypox virus has two evolutionary branches, and the mortality of one branch may reach 10%! However, there are still many unknowns about monkeypox. The who found that “male behavior” is a new clue
News from overseas network shows that the United States has ordered more than $100 million and millions of doses of monkeypox vaccineP align = “center” distribution map of monkeypox epidemic in the UK as of May 19 p align = “center” source: Huashan infection
Although there have been no cases in China, it is an indisputable fact that monkeypox virus has broken out in Europe and America. How should ordinary people deal with it?
On the morning of May 21, Huashan Hospital Affiliated to Fudan University issued a document, believing that the risk of monkeypox virus imported into China will continue to exist. It is suggested that relevant departments should prepare for possible imported cases
there are 80 cases in the world
countries found monkeypox cases are “atypical”
According to China Central Television News, the World Health Organization said on the 20th that recently, the organization has received reports from many countries about 80 monkeypox cases, and another 50 cases need to be confirmed in many non monkeypox endemic countries, monkeypox cases are found to be “atypical”.
Overseas network news pointed out that on May 6, the UK first confirmed the first case of monkeypox this year, the UK health and Safety Bureau issued a statement that may be transmitted through the community
Subsequently, confirmed or suspected cases were also found in several countries:
Canada public health department said on May 20 local time that Quebec has confirmed 3 monkeypox cases . So far, the number of monkeypox cases confirmed in Canada has reached 5 , all located in Quebec.
In addition, the public health department is still investigating more than 20 other suspected cases in Quebec. It is reported that this disease has never been found in Canada before, and a confirmed case of monkeypox in the United States recently traveled to Quebec, Canada.
Netherlands National Institute of health and environment announced on the 20th local time that one case of monkeypox virus infection and several suspected cases had been confirmed in the country on the same day.
On the 20th local time, UK reported 11 new cases of monkeypox, with a total of 20 confirmed cases.
Spain’s Ministry of Health said that the National Microbiology Center tested positive for 23 suspected monkeypox cases, which means that the cumulative number of monkeypox cases in the country has reached 30 , and all confirmed cases come from Madrid. According to the Madrid regional health authorities, all confirmed cases are male, with an average age of about 35.
Germany Munich federal Defense Forces Institute of Microbiology said on the 20th that a patient in Bavaria, Germany was infected with monkeypox, which was the first confirmed case of monkeypox in Germany .
On May 20 local time, Australia NSW and Victoria health departments confirmed that a case of monkeypox was found in each state. Both cases have recently arrived in Australia from Europe and have mild symptoms after infection. At present, they have been isolated.
On May 18 local time, Portugal health authorities confirmed 5 monkeypox cases, and 15 suspected cases are still under investigation. These cases are male and their skin is damaged.
On May 18 local time, the United States centers for Disease Control and Prevention confirmed the first case of monkeypox in the United States this year.
On May 21, according to the financial associated press report, Russia health minister murashko said that at present no cases of monkeypox virus infection have been found in Russia . Thanks to vaccination before 1980, some Russians have immunity to monkeypox virus.
The series of cases were described by experts as “unusual” and “surprising”. “this outbreak is very rare,” epidemiologist Susan Hopkins, chief medical adviser to the UK health and Safety Agency (ukhsa), said in a statement
who: there are many unknowns about monkeypox. “Male behavior” is a new clue
Ibrahima souse farle, assistant director general for emergency response of the World Health Organization, said at the organization’s press conference a few days ago that monkeypox is mainly prevalent in West and Central Africa, and most cases are found in Nigeria, the Democratic Republic of the Congo, the Central African Republic and other countries.
For example, the DRC reported more than 6000 cases in 2020 and more than 3000 cases in 2021; The number of cases in Nigeria is also increasing this year, mainly in rural areas.
At present, there are still many unknowns about the transmission mode, clinical characteristics and epidemiology of monkeypox, and there are still gaps in treatment and diagnosis.
On the monkeypox cases reported in the UK, he said that the who was in close communication with the regional office, the UK public health department and partners to monitor not only those who had contact with cases with a travel history in Nigeria, but also cases transmitted in the UK.
according to Xinhuanetco.Ltd(603888) , who has noticed the spread of monkeypox among men who have sex with men, which is a new clue , and correct investigation is needed to better understand the local transmission dynamics in the UK and some other countries.
Surging News reported that “many monkeypox cases worldwide have been reported in sexual networks.” Dr inger Damon, director of the Department of pathogens and pathology at the CDC, said in a press release. However, the Centers for Disease Control and prevention also said that monkeypox has not been recognized as a sexually transmitted disease, but it can be transmitted through close contact with infected people, their body fluids, clothes or bed sheets.
Michael Ryan, executive director of the WHO health emergency program, said that the epidemiology of monkeypox has changed and its scope has expanded in the past few years
In West Africa and the Sahel, climate pressure is increasing and agricultural practices are changing. In many cases, human beings have to adapt to the environment in order to survive. At the same time, small animals and rodents are also adapting to the environment. They are in the same drought and food crisis, which makes animal populations closer to humans and sometimes compete for the same food resources.
He stressed that must really understand the deep ecology and human behavior in the above areas, should involve and empower communities to understand how the disease spreads, and then try to stop the disease from spreading to humans from the source of nature.
Huashan article: rare monkeypox epidemic in Europe and America
should we worry
On the 21st, the wechat official account “Huashan infection” of Huashan Hospital Affiliated to Fudan University published article.
The article points out that although there have never been any confirmed cases of monkeypox in China, the infectious disease has no national boundaries and the risk of monkeypox virus importing into China will continue to exist, and with the outbreak in Europe and the United States, the risk of imported cases in China will increase accordingly
Since China stopped vaccinating against smallpox (cowpox) in the early 1980s, at present, people under the age of 40 are generally not immune to smallpox and monkeypox
While paying close attention to the international epidemic situation of monkeypox, we should make preparations in advance, carry out public science popularization and publicity of monkeypox, strengthen the monitoring of cases with similar symptoms, and develop diagnostic methods and reagents, so as to find imported cases in time, block the transmission and prevent the prevalence of monkeypox in China.
At the same time, should start to reserve specific vaccines and antiviral drugs to avoid being in a passive situation after cases
what is monkeypox
smallpox virus “close relatives”
According to the health times, monkeypox is an acute infectious disease caused by monkeypox virus from the perspective of etiology, monkeypox virus and smallpox virus belong to the family of orthopoxviridae , and their infectivity and pathogenicity are weaker than smallpox virus, which is also one of the factors that arouse people’s vigilance.
In 1958, monkeypox virus was first found in monkeys, so it was named monkeypox, but now rodents are also regarded as possible main animal hosts.
In 1970, the first human case of monkeypox infection was found in the Democratic Republic of the Congo. Since then, monkeypox outbreaks have occurred many times in West African countries.
The main mode of transmission of monkeypox virus is through direct contact with the blood, body fluid, skin or mucosal wound of infected animals
The secondary transmission between humans is mainly due to close contact with the respiratory secretions and skin damage of the infected person, or articles contaminated by the patient’s body fluid or diseased tissue (such as clothes and sheets contaminated by the liquid flowing out after the patient’s skin rash breaks).
monkeypox virus can exist in respiratory droplets, but it usually requires long-term face-to-face contact to spread
The incubation period of monkeypox can reach 5-21 days. In the early stage of onset, the symptoms of the patient include fever, headache, muscle pain, back pain, enlarged lymph nodes and so on.
Usually, within 1-3 days after fever, patients will have different degrees of rash, which will spread from the face to other parts of the body. The rash evolved from a flat maculopapular rash to a small blister filled with liquid to an pustule. The scab formed after about 10 days and disappeared after about three weeks. When a rash occurs, the patient is infectious.
is not a severe infectious disease, and the possibility of pandemic is small
“Everyone knows that smallpox is a severe infectious disease. It’s terrible. Monkeypox is related to it. Is it as terrible as it?” Shen Jun, deputy chief physician of the infection department of the pediatric hospital affiliated to Fudan University, told the health times that smallpox is the only infectious disease eliminated by mankind, but unlike monkeypox, monkeypox itself is not a severe infectious disease, has not appeared in China, and has not been included in China’s routine infectious disease monitoring report
Ren Hong, chief expert of the national major infectious diseases project, told the health times that interpersonal transmission is very rare. At present, the cases reported in various countries are mainly sporadic, and it is difficult to trace the source but there is little chance of a pandemic
no specific drugs, but patients can heal themselves
“At present, there is no specific drug for monkeypox. Just like covid-19, there are no specific drugs for many viral diseases.” Shen Jun told the health times, but it is a self limiting disease. Generally, patients will heal themselves by producing autoantibodies , and the symptoms will be reported. Clinically, it is mainly symptomatic support treatment.
Rest, replenish water and nutrition. Strengthen personal care and keep eyes, nose, mouth and skin clean. Antibiotics can be used to prevent secondary infection when necessary.
how to prevent monkeypox virus
Common household disinfectants can kill monkeypox virus.
Avoid contact with animals that may carry the virus. In addition, after contacting infected people or animals, wash hands with soapy water or use alcoholic hand sanitizer. It is also recommended to wear protective equipment when taking care of patients.
monkeypox virus is the “close relative” of human smallpox virus , but the symptoms of monkeypox infection are mild. Smallpox vaccine can also prevent monkeypox, and the effective rate is about 85%.
US media: the US government has ordered millions of doses of monkeypox Vaccine
According to overseas network reports, after the United States reported its first case of monkeypox infection this year, the US media Newsweek reported on the 19th that the US health department had ordered millions of doses of monkeypox vaccine worth US $119 million
On the 18th, Bavarian Nordic, a Danish vaccine company, said in a statement that it had signed a contract worth hundreds of millions of dollars with the US biomedical advanced research and Development Agency (BARDA).
In addition to vaccines, the U.S. Department of defense signed a $7.5 million contract with pharmaceutical companies last week to purchase an antiviral treatment for monkeypox.
concept stocks, which soared 43%
In the context of the outbreak in many countries, “monkeypox” has also triggered a shock in the capital market.
On Friday, Shanghai Zj Bio-Tech Co.Ltd(688317) rose sharply to the “20cm” limit. As of the close, Shanghai Zj Bio-Tech Co.Ltd(688317) rose 16.34%. In addition, Daan Gene Co.Ltd(002030) , master biology, etc. also rose sharply.
in addition to A-share listed companies, US stocks also have related concept stock changes
On May 20 local time, US stocks of biopharmaceuticals developing therapeutic drugs and vaccines for smallpox rose. As of the close, SIgA technologies rose 43.35%, emergency biosolution rose more than 11.49%, and tonix pharmaceuticals rose 14.93%.
At present, in the A-share market, it is reported that Shanghai Zj Bio-Tech Co.Ltd(688317) products have monkeypox virus nucleic acid determination kit (fluorescence PCR method). However, Shanghai Zj Bio-Tech Co.Ltd(688317) has not responded to this.
Daan Gene Co.Ltd(002030) has reserves of monkeypox virus related scientific research products, but there is no relevant certified reagent at present.
In addition, Jiangsu Bioperfectus Technologies Co.Ltd(688399) official website shows that the company has monkeypox virus nucleic acid detection kit (fluorescence PCR method), article number jc70115 However, according to media reports, the company has not obtained a registration certificate for this product, which is only used for Disease Control and scientific research.
clarification of several A-share companies
The stock price changes of related concept stocks have also aroused strong concern of investors. According to the reporter of the securities times, 58 relevant questions and answers were searched on the interactive platform of Shenzhen Stock Exchange and Shanghai Stock Exchange e with the keyword “monkeypox”. Among them, many companies clarified that they did not have relevant products.
For example, Hualan Vaccine said that the company has no vaccine products to prevent monkeypox and smallpox.
Changchun High And New Technology Industries (Group) Inc(000661) indicates that the company and its subsidiaries have no monkeypox vaccine related products for the time being.
Daan Gene Co.Ltd(002030) indicates that the company has reserves of monkeypox virus related scientific research products, but there is no relevant certified reagent at present.
Zhejiang Yongtai Technology Co .Ltd(002326) in response to the investor’s question “can the company’s products directly or indirectly synthesize smallpox vaccine?” Said the company did not produce vaccines.
Hainan Shuangcheng Pharmaceuticals Co.Ltd(002693) said that the company also noticed the “monkeypox disease”. Because the pathogenesis and other information are not clear at present, the company has no drugs for this indication.
Wuhan Easy Diagnosis Biomedicine Co.Ltd(002932) said that the company has no monkeypox testing business.
Jinyu Bio-Technology Co.Ltd(600201) said that the company has carried out research and development activities on poxvirus related vaccines such as goat pox and bovine nodular skin disease, and monkeypox virus is not involved at present.
Changchun Bcht Biotechnology Co(688276) said that the company’s varicella vaccine could not prevent monkeypox, and the company did not have products related to monkeypox virus prevention.
